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Effect of subdiaphragmatic vagotomy on production of gastric ulcers in pylorus-ligated albino rats

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Summary

A reduction in volume and free and total acidity of gastric content was noted along with reduction in ulcer index, with a shift of the site of ulceration from fundus to the glandular part of stomach, following vagotomy in pylorus-ligated rats. Low volume and acidity explains the absence of ulcers in the fundus, but the increased involvement of glandular part in ulceration is possibly due to weakening of the mucosal barrier following vagotomy.

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Authors and Affiliations

  1. Department of Physiology, Jawaharlal Institute of Post-Graduate Medical Education and Research, Pondicherry-6, India

    A. K. Ganguly & S. K. Lal

Authors
  1. A. K. Ganguly
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  2. S. K. Lal
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Ganguly, A.K., Lal, S.K. Effect of subdiaphragmatic vagotomy on production of gastric ulcers in pylorus-ligated albino rats. Experientia 32, 74–75 (1976). https://doi.org/10.1007/BF01932631

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