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Adenovirus type 12 infection of defined mouse-human hybrid cell clones

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Summary

Human adenovirus type 12 does not multiply in mouse cells; only viral T-antigen is detected. Mouse-human cell hybrid clones containing human chromosomes A3, B5, C7, C11, C12, D14, E17, F19 and F20, support synthesis of adenovirus DNA and capsid antigens.

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Authors and Affiliations

  1. Department of Microbiology, College of Medicine and Dentistry of New Jersey, Rutgers Medical School, 08854, Piscataway, New Jersey, USA

    K. K. Biron & K. Raska Jr.

Authors
  1. K. K. Biron
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  2. K. Raska Jr.
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Additional information

The hybrid clones used in these experiments were kindly supplied by Drs.Carlo Croce andHilary Koprowski of the Wistar Institute, Philadelphia, Pennsylvania. Supported by Grants from National Cancer Institute.

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Biron, K.K., Raska, K. Adenovirus type 12 infection of defined mouse-human hybrid cell clones. Experientia 32, 38–40 (1976). https://doi.org/10.1007/BF01932611

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