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Intense sweetener from Lo Han Kuo (Momordica grosvenori)

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Zusammenfassung

Die getrockneten Früchte, Lo Han Kuo, vonMomordica grosvenori Swingle, enthalten einen Süss-Stoff, der mit Hilfe von Dünnschicht-Chromatographie abgesondert wurde.

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Literatur

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  3. W. T. Swingle, J. Arnold Arboretum22, 198 (1941). I am grateful to Dr.Shiu Ying Hu of harvard University for supplying this reference.

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  4. The paper bySwingle 3 noted the intense sweet taste of Lo Han Kuo pulps, but no mention was made of the taste of its rinds. It is quite noteworthy that the rinds also contain the sweetener.

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  6. Male albino mice (Charles River Laboratory) weighing 19–24 g were dosed orally with aqueous solutions of the lyophilized extracts at a volume of 0.3 ml/10 g body weight and were kept for observation for 1 week. A very crude extract (without any processing) as well as the Sephadex G-25 treated extract were tested with 10 animals per group. None of the mice died. At a dose of 15 g crude extract per kg mice, the animals exhibited a mild sedation and some diarrhea; however, these effects were transient as all animals appeared normal within 30–60 min. I thankP. Holmes andA. Pritchard for these results.

  7. The technical assistance ofJ. Weinberger is appreciated.

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Lee, CH. Intense sweetener from Lo Han Kuo (Momordica grosvenori). Experientia 31, 533–534 (1975). https://doi.org/10.1007/BF01932442

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  • DOI: https://doi.org/10.1007/BF01932442

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