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Is ATP synthesized by a vacuolar-ATPase in the extremely halophilic bacteria?

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Abstract

The proton-dependent synthesis of ATP was demonstrated in representative members of the generaHalobacterium, Haloarcula, andHaloferax. In all cases, synthesis was not inhibited by nitrate or N-ethylmaleimide, inhibitors of the vacuolar-like ATPase found in Archaea, but was affected by azide, an inhibitor of F0F1-ATP syntheses. These observations extend the earlier observations withHalobacterium saccharovorum and suggest that ATP synthesis in these organisms is brought about by an F0F1-APT synthase.

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  1. Ames Research Center, 95035-1000, Moffett Field, California, USA

    L. I. Hochstein & D. Lawson

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  1. L. I. Hochstein
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  2. D. Lawson
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Hochstein, L.I., Lawson, D. Is ATP synthesized by a vacuolar-ATPase in the extremely halophilic bacteria?. Experientia 49, 1059–1063 (1993). https://doi.org/10.1007/BF01929914

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