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Estrogen target cells in the skin

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Zusammenfassung

Nach Injektion von3H-Östradiol wurden Retention und Konzentration des Hormons in Zellen der Keimschicht der Epidermis und in Fibroblasten der Dermis und Hypodermis von Mäusen gefunden. Zellen der Haarpapillen in den Haarwurzeln zeigten starke nukleäre Radioaktivität, während in der basalen Zellschicht der Talgdrüsen keine oder nur schwache Markierung beobachtet werden konnte. Diese Ergebnisse mit der Trocken-Autoradiographie demonstrieren erstmalig die Existenz von verschiedenen Populationen von Östradiol-Targetzellen in der Haut.

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Literatur

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Authors and Affiliations

  1. Laboratories for Reproductive Biology, Departments of Anatomy and Pharmacology, University of North Carolina, 111 Swing Building, 27514, Chapel Hill, North Carolina, USA

    W. E. Stumpf, Madhabananda Sar & S. G. Joshi

  2. Department of Obstetrics and Gynecology, Albany Medical College of Union University, 12208, Albany, New York, USA

    W. E. Stumpf, Madhabananda Sar & S. G. Joshi

Authors
  1. W. E. Stumpf
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  2. Madhabananda Sar
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  3. S. G. Joshi
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Additional information

This study was supported by PHS Grant No. NS 09914. We thank Ms.Anu Turnbull andGerda Michalsky for technical assistance.

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Stumpf, W.E., Sar, M. & Joshi, S.G. Estrogen target cells in the skin. Experientia 30, 196–198 (1974). https://doi.org/10.1007/BF01927732

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