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9α-fluoro-11β-hydroxybenzo [d, e] testosterone 17-acetate. A modified steroid highly active on DMBA-induced mammary tumors in rats

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Riassunto

È stato preparato un nuovo analogo pentaciclico del testosterone e ne sono state saggiate le proprietà ormonali e l'attività nel test del tumore mammario indotto dal DMBA nel ratto. Il conposto ha dimostrato un'elevata attività antitumorale e una scarsa attività androgena.

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Author notes

  1. G. Briziarelli

    Present address: Warner-Lambert Research Institute, Morris Plains, New Jersey, USA

  2. P. P. Castelli

    Present address: Istituto Lark per le Ricerche Mediche, San Giuliano Milanese, Italy

Authors and Affiliations

  1. Warner-Vister Steroid Research Institute, I-22064, Casatenovo, Como, Italy

    G. Briziarelli, P. P. Castelli, R. Vitali & R. Gardi

Authors
  1. G. Briziarelli
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  2. P. P. Castelli
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  3. R. Vitali
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  4. R. Gardi
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Briziarelli, G., Castelli, P.P., Vitali, R. et al. 9α-fluoro-11β-hydroxybenzo [d, e] testosterone 17-acetate. A modified steroid highly active on DMBA-induced mammary tumors in rats. Experientia 29, 618–619 (1973). https://doi.org/10.1007/BF01926703

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  • DOI: https://doi.org/10.1007/BF01926703

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