Skip to main content
Log in

Interaction between β-adrenergic stimulant and phosphodiesterase inhibiting drugs on the bronchial muscle

  • Published:
Experientia Aims and scope Submit manuscript

Riassunto

È stato dimostrato che la contemporanea stimolazione delle adenilciclasi, realizzata con salbutamolo, e la inibizione delle fosfodiesterasi prodotta da teofilina esercitano, effetti broncodilatatori sinergici. Il potenziamento osservato anche fra salbutamolo e dibutirril-3′5′ AMP è stato riferito alla inibizione delle fosfodiesterasi determinata da quest' ultima sostanza.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Y. Vulliemoz, M. Verosky, G. G. Nahas andL. Triner, Pharmacologist73, 256 (1971).

    Google Scholar 

  2. A. Bertelli, B. Bianchi andL. Beani, J. Pharm. Pharmac.,25, 60 (1973).

    Article  CAS  Google Scholar 

  3. R. T. Brittain, J. B. Farmer, D. Jack, L. E. Martin andW. T. Simpson, Nature, Lond.219, 862 (1968).

    Article  CAS  PubMed  Google Scholar 

  4. D. Hartley, D. Jack, L. H. C. Lunts andA. C. Ritchie, Nature, Lond.219, 861 (1968).

    Article  CAS  PubMed  Google Scholar 

  5. P. L. Kamburoff andF. J. Prim, Br. J. Dis. Chest.64, 46 (1968).

    Article  Google Scholar 

  6. C. A. Menham, K. D. Hepp andO. Wieland, Eur. J. Biochem.,8, 435 (1969).

    Google Scholar 

  7. A. Lucacchini, V. Montali, M. Ranieri andC. A. Rossi, Boll. Soc. ital. Biol. sper.48, 17 (1972).

    CAS  PubMed  Google Scholar 

  8. H. Konzett, andR. Rössler, Arch. exp. Path. Pharmak.195, 71 (1940).

    Article  Google Scholar 

  9. A. Akasu, Archs int. Pharmacodyn.122, 201 (1959).

    Google Scholar 

  10. G. A. Robison, R. W. Butcher andE. W. Sutherland,Cyclic AMP (Academic Press, New York 1971).

    Google Scholar 

  11. P. Greengard andE. Costa,Role of Cyclic AMP in Cell Function (Raven Press, New York 1970).

    Google Scholar 

  12. Acknowledgments: We thank Mr.A. Giacomelli for the technical assistance.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Bertelli, A., Bianchi, C. & Beani, L. Interaction between β-adrenergic stimulant and phosphodiesterase inhibiting drugs on the bronchial muscle. Experientia 29, 300–302 (1973). https://doi.org/10.1007/BF01926489

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01926489

Keywords

Navigation