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Prostaglandin feedback mechanism limits vasoconstrictor action of norepinephrine in perfused rabbit ear

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Zusammenfassung

Durch Noradrenalin ausgelöste Vasokonstriktion am perfundierten Kaninchenohr ist begleitet von der Freisetzung eines PGE-ähnlichen Stoffs, welcher für die Entwicklung der akuten Toleranz gegenüber der vasokonstriktorischen Wirkung von Noradrenalin verantwortlich ist.

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Authors and Affiliations

  1. Department of Pharmacology, Copernicus Medical Academy, 16 Grzegorzecka, 31-531, Krakow, Poland

    R. J. Gryglewski & R. Korbut

Authors
  1. R. J. Gryglewski
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  2. R. Korbut
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Additional information

The authors gratefully acknowledge the supply with prostaglandins by Dr.J. Pike, Upjohn Co, Kalamazoo, USA.

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Gryglewski, R.J., Korbut, R. Prostaglandin feedback mechanism limits vasoconstrictor action of norepinephrine in perfused rabbit ear. Experientia 31, 89–91 (1975). https://doi.org/10.1007/BF01924695

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