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A potent antihypercholesterolemic agent: [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14643)

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Zusammenfassung

Es wird die Synthese von [4-Chlor-6-(2, 3-xylidino)-2-pyrimidinylthio]-essigsäure und seine antihypercholesterolämische Aktivität beschrieben.

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Reference

  1. W. L. Bencze, R. Hess andG. DeStevens, Progr. drug Res.13, 217 (1969).

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  2. R. M. Tomarelli, T. M. Dougherty andF. W. Bernhart, J. pharm. Sci.55, 1392 (1966).

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Authors and Affiliations

  1. Research Division, Wyeth Laboratories, Inc., 19087, Radnor, Pennsylvania, USA

    A. A. Santilli, A. C. Scotese & R. M. Tomarelli

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  1. A. A. Santilli
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  2. A. C. Scotese
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  3. R. M. Tomarelli
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Santilli, A.A., Scotese, A.C. & Tomarelli, R.M. A potent antihypercholesterolemic agent: [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14643). Experientia 30, 1110–1111 (1974). https://doi.org/10.1007/BF01923636

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  • DOI: https://doi.org/10.1007/BF01923636

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