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Possible influence of prolactin on intestinal hypertrophy in pregnant and lactating rats

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Summary

The increase in intestinal weights during lactation, and to a lesser extent during pregnancy, is inhibited by bromocriptin. This suggests that increased prolactin secretion might be responsible for gut hypertrophy during lactation.

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Author notes

  1. J. R. Mainoya

    Present address: Department of Zoology, University of Dar es Sallaam, P.O. Box 35064, Dar es Salaam, Tanzania

Authors and Affiliations

  1. Department of Zoology and Cancer Research Laboratory, University of California, 94720, Berkeley, California, USA

    J. R. Mainoya

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  1. J. R. Mainoya
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Additional information

This work was supported by N.I.H. grant Ca-05388 and a Rockefeller Foundation Fellowship.

The author is very grateful to Professor H.A. Bern for his useful suggestions. Professor E. Flückiger, Sandoz Ltd, kindly supplied the bromocriptin used in this study.

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Mainoya, J.R. Possible influence of prolactin on intestinal hypertrophy in pregnant and lactating rats. Experientia 34, 1230–1231 (1978). https://doi.org/10.1007/BF01922975

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