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Effects of postnatal progesterone treatment on ovarian function in adult rats

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Summary

Long-lasting postnatal progesterone administration in female rats induced an early or delayed ovulatory failure with persistent vaginal estrus. Short-term treatment was ineffective. The beginning and incidence of ovulatory failure appeared to depend on the beginning and duration of progesterone treatment. The necessary duration of progesterone administration exceeds the critical postnatal steroid sensitive period of sexual differentiation of the hypothalamus. Moreover, long-lasting progesterone treatment results in ovulatory failure even if started after termination of this period.

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References

  1. R.A. Gorski, Endocrinology82, 1001 (1968).

    Article  CAS  PubMed  Google Scholar 

  2. N. Takasugi, J. Fac. Sci. Univ. Tokyo, Sect. IV Zool.7, 299 (1954).

    Google Scholar 

  3. R.I. Dorfman and F.A. Kincl, IV Reunión Anual Soc. Mex. Nut. Endocr. Ixtapan de la Sal, México, 6–7 December 1963, p. 171.

  4. E.G. Shipley and R.K. Meyer, in: Hormonal Steroids, vol. 2, p. 293. Ed. L. Martini and A. Pecile. Academic Press, New York 1965.

    Google Scholar 

  5. J. Presl and A. Bukovský, Čslka Gynek.41, 449 (1976).

    CAS  Google Scholar 

  6. G. Shipley and K. Meyer, Int. Congr. Hormonal Steroids, Milan, Italy, 14–19 May, 1962, p. 86.

  7. F.A. Kincl, A. Folch Pi and L. Herrera Lasso, Ciencia, Méx.22, 135 (1963).

    Google Scholar 

  8. J. Presl, J. Jirásek, I. Mikuláš and J. Horský, Čslka Gynek.32, 658 (1967).

    CAS  Google Scholar 

  9. R.R. Greene and M.W. Burrill, Am. J. Physiol.133, P302 (1941).

    Google Scholar 

  10. N. Takasugi, Annotnes zool. jap.26, 52 (1953).

    Google Scholar 

  11. N. Takasugi, Annotnes zool. jap.26, 91 (1953).

    Google Scholar 

  12. A. Bukovský, J. Presl and Z. Krabec, Čslka Gynek.41, 281 (1976);

    Google Scholar 

  13. J. Presl, V. Figarová, J. Herzmann and S. Röhling, Endocr. exp.9, 51 (1975).

    CAS  Google Scholar 

  14. J. Presl, J. Herzmann and S. Röhling, Čslka Gynek.40, 751 (1975).

    CAS  Google Scholar 

  15. A. Bukovský and J. Presl, Med. Hypotheses4, in press (1978).

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Authors and Affiliations

  1. Institute for the Care of Mother and Child, nábř. K. Marxe 157, CS-147 10, Praha 4-Podolí, Czechoslovakia

    A. Bukovský, J. Presl & Z. Krabec

Authors
  1. A. Bukovský
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  2. J. Presl
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  3. Z. Krabec
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Bukovský, A., Presl, J. & Krabec, Z. Effects of postnatal progesterone treatment on ovarian function in adult rats. Experientia 35, 562–563 (1979). https://doi.org/10.1007/BF01922773

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