Summary
In concentrations that produced synaptic blockade in the squid giant synapse, sodium pentobarbital produced a dose-related, reversible decrease of the ‘calcium spike’ of the presynaptic terminal.
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This work was performed while Dr Morgan was a Grass Foundation Fellow at the Marine Biological Laboratory, Woods Hole, Massachusetts, USA.
The authors thank Dr J. Z. Yeh for the loan of the 4-aminopyridine and Dr G. H. Acheson for helpful suggestions.
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Morgan, K.G., Bryant, S.H. Pentobarbital: Presynaptic effect in the squid giant synapse. Experientia 33, 487–488 (1977). https://doi.org/10.1007/BF01922226
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DOI: https://doi.org/10.1007/BF01922226