Summary
Sensitized peritoneal exudate cells from Swiss albino mice donors infected with a single dose of 1000A. caninum larvae could expel a challenge dose of 500 larvae from recipients at a faster rate when compared to cells from repeatedly infected (250+250+500) donors. However, at 36 h after challenge, the larval expulsion was almost the same in both the groups. Because of the bowel sensitization by the cells, some larvae (not expelled) in the 1st group, readily migrated into muscles where they met allergic immobilization and death due to infiltration of inflammatory cells and their exudates at these sites.
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Acknowledgment. We thank Professor H. Swarup for providing facilities and to the Council of Scientific and Industrial research, New Delhi for financial assistance.
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Vardhani, V., Johri, G.N. Rejection of worm load through singly and repeatedly sensitized peritoneal exudate cells during experimental ancylostomiasis. Experientia 34, 122–123 (1978). https://doi.org/10.1007/BF01921940
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DOI: https://doi.org/10.1007/BF01921940