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The formation of disulfide bonds in human protamines during sperm maturation

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Summary

The disulfide contents of human sperm heads, as measured by reduction to the sulfhydryls and subsequent alkylation with14C-iodoacetamide, increase about 2-fold during the sperm passage from the caput to caudal epididymides. Majority of the increased disulfides reside in the human protamine fractions.

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We thank Drs Jisnuson Svasti and Nongnuj Tanphaichitr for their valuable suggestions. This work was supported by the Faculty of Science, Mahidol University, and the Rockefeller Foundation.

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Saowaros, W., Panyim, S. The formation of disulfide bonds in human protamines during sperm maturation. Experientia 35, 191–192 (1979). https://doi.org/10.1007/BF01920608

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