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The role of myocardial edema in the left ventricular diastolic stiffness

Die Bedeutung des Myokardödems für die diastolische Steifheit des linken Ventrikels

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Summary

It has been shown that simultaneous administration of norepinephrine (10 μg/kg/min) and drotaverine (200 μg/kg/min) does induce interstitial myocardial edema which tends to increase left ventricular diastolic stiffness. These results suggest that in myocardial ischaemia temporary increase of left ventricular diastolic stiffness may be caused by interstitial edema.

Zusammenfassung

Es wurde bewiesen, daß die gleichzeitige, intravenöse Verabreichung von Noradrenalin (10 μg/kg/min) und Drotaverin (200 μg/kg/min) ein vorübergehendes interstitielles Myokardödem hervorruft, das zur diastolischen Erhöhung der linken Herzkammerwandsteifheit führt. Die Beobachtung läßt vermuten, daß die bei Myokardischämie zeitweilig in Erscheinung tretende, diastolische Erhöhung der linken Kammerwandsteifheit durch ein vorübergehendes, interstitiales Gewebsödem verursacht werden kann.

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Author notes

  1. G. Pogátsa

    Present address: Fourth Medical Department of the Semmelweis, Medical University, Budapest, Hungary

Authors and Affiliations

  1. Fourth Medical Department of the Semmelweis, Medical University, Budapest, Hungary

    E. Dubecz & Gy. Gábor

  2. Hungarian Institute of Cardiology, Budapest, Hungary

    G. Pogátsa, E. Dubecz & Gy. Gábor

Authors
  1. G. Pogátsa
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  2. E. Dubecz
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  3. Gy. Gábor
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With 3 figures and 1 table

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Pogátsa, G., Dubecz, E. & Gábor, G. The role of myocardial edema in the left ventricular diastolic stiffness. Basic Res Cardiol 71, 263–269 (1976). https://doi.org/10.1007/BF01906451

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  • DOI: https://doi.org/10.1007/BF01906451

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