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Effect of calcitonin on glycosaminoglycan synthesis by embryo calf bone cells in vitro

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  • Physiologica
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Zusammenfassung

Es wurde gefunden, dass rohe Calcitoninpräparate die Inkorporation von14C-Glucose in die Glycosaminoglycan-(GAG)-Synthese fördern. Unter denselben Zellkulturbedingungen wurde Calcitonin mit stark spezifischer Aktivität rasch inaktiviert und zeigte keine stimulierende Wirkung; wurde aber der Serumgehalt im Milieu stark eingeschränkt, so verursachte das Calcitonin (50 Einheiten/mg) eine hundertprozentige Erhöhung der14C-GAG-Synthese.

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Authors and Affiliations

  1. Department of Medicine, The Royal Melbourne Hospital, University of Melbourne, 3050, Parkville, Victoria, Australia

    T. J. Martin, G. S. Harris, R. A. Melick & J. R. E. Fraser

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  1. T. J. Martin
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  2. G. S. Harris
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  3. R. A. Melick
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  4. J. R. E. Fraser
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Martin, T.J., Harris, G.S., Melick, R.A. et al. Effect of calcitonin on glycosaminoglycan synthesis by embryo calf bone cells in vitro. Experientia 25, 375–376 (1969). https://doi.org/10.1007/BF01899928

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  • DOI: https://doi.org/10.1007/BF01899928

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