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Biosynthesis of plant sterols. Conversion of cholesterol to pregnenolone inDigitalis purpurea

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Résumé

Un échantillon purifié de cholestérol-4-C14 a été absorbé par des feuilles de 2 plantes deDigitalis purpurea. Après 18 jours on a extrait les plantes et séparé les composés radioactifs. Environ 1% des métabolites globales a été constaté en forme de pregnénolone. Ainsi le cholestérol peut agir comme précurseur des stérols végétaux.

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Author notes

  1. K. V. Thimann

    Present address: University of California, Santa Cruz, California

  2. A. Winter

    Present address: York University, York, England

Authors and Affiliations

  1. Worcester Foundation for Experimental Biology, Shrewsbury and Harvard University, Cambridge, Massachusetts, USA

    E. Caspi, D. O. Lewis, D. M. Piatak, K. V. Thimann & A. Winter

Authors
  1. E. Caspi
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  2. D. O. Lewis
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  3. D. M. Piatak
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  4. K. V. Thimann
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  5. A. Winter
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Additional information

This work was supported by Grants No. CA-07137, No. A-5326 and No. FR-05528 from the U.S. Public Health Service, and No. G-21799 from the National Science Foundation.

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Caspi, E., Lewis, D.O., Piatak, D.M. et al. Biosynthesis of plant sterols. Conversion of cholesterol to pregnenolone inDigitalis purpurea. Experientia 22, 506–507 (1966). https://doi.org/10.1007/BF01898654

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  • DOI: https://doi.org/10.1007/BF01898654

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