Summary
Polymorphism of the A subunit of human coagulation factor XIII was investigated in a total of 561 plasma samples from unrelated adult Japanese using an agarose gel electrophoresis followed by a fluorescent technique for the localization of transglutaminase activity. Three common phenotypes were observed, which corresponded to the types 1, 2-1 and 2 reported by Board (1979) in Australians. The family material from 23 matings with 60 children indicated that these phenotypes are controlled by a pair of autosomal, codominant alleles. The estimated allele frequencies ofF13A *1 andF13A *2 were 0.887 and 0.113, respectively.
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Nishigaki, T., Omoto, K. & Juji, T. Genetic polymorphism of the a subunit of human coagulation factor XIII in Japanese. Jap J Human Genet 26, 237–241 (1981). https://doi.org/10.1007/BF01896135
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DOI: https://doi.org/10.1007/BF01896135
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