Abstract
Enterolobin, a 55-kDa cytolytic, inflammatory, and insecticidal protein isolated from seeds of the Brazilian treeEnterolobium contortisiliquum (Leguminosae-Mimosoideae) has been further purified and partially sequenced by using both manual and automated methods. A computational search of enterolobin partial amino acid sequence against the PIR database revealed possible sequence similarities with aerolysins, cytolytic proteins fromAeromonas species. An alignment of enterolobin partial sequence to the amino acid sequences ofA. hydrophila andA. sobria aerolysins showed several similar regions with many residue identites. The seed protein enterolobin and the bacterial aerolysins may be homologous proteins despite the distant phylogenetic relationship.
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Sousa, M.V., Richardson, M., Fontes, W. et al. Homology between the seed cytolysin enterolobin and bacterial aerolysins. J Protein Chem 13, 659–667 (1994). https://doi.org/10.1007/BF01886950
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DOI: https://doi.org/10.1007/BF01886950