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Bile duct strictures associated with hepatic arterial infusion chemotherapy

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Abstract

We report 6 cases of bile duct strictures in patients receiving intraarterial floxuridine chemotherapy for metastatic colon carcinoma. The computed tomographic and cholangiographic features of these cases mimic those seen with primary sclerosing cholangitis. The postulated mechanism for development of biliary strictures is direct toxicity and/or occlusion of the peribiliary vascular plexus with resultant biliary fibrosis.

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  1. Department of Radiology, University Hospital, University of Cincinnati Medical Center, 234 Goodman Street, M.L. 742, 45267, Cincinnati, OH, USA

    Robert A. Clark M.D. & Thomas E. Gallant

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  1. Robert A. Clark M.D.
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  2. Thomas E. Gallant
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Clark, R.A., Gallant, T.E. Bile duct strictures associated with hepatic arterial infusion chemotherapy. Gastrointest Radiol 12, 148–151 (1987). https://doi.org/10.1007/BF01885126

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  • DOI: https://doi.org/10.1007/BF01885126

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