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Classification ofα 2-HS-glycoprotein (α 2HS) types by isoelectric focusing

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Summary

A sample of 300 sera from unrelated individuals from Northern Japan was examined by isoelectric focusing on polyacrylamide gels. Three common types,α 2HS 1-l, 2-1, and 2-2 were differentiated. The frequencies of theα 2HS alleles in our sample were found to be:α 2HS1=0.7250 andα 2HS2= 0.2750. Analysis of 16 parents with 21 children did not show deviations from the expected mode of inheritance.

Zusammenfassung

Mit Hilfe der isoelektrischen Fokussierung in Polyacrylamidgelen wurden 300 Proben von nicht verwandten Personen aus Nordjapan untersucht. Es wurden drei häufige Gruppen,α 2HS 1-1, 2-1 und 2-2 differenziert. Die Allelfrequenzen in dieser Stichprobe betrugen:α 2HS1= 0,7250 undα 2HS2=0,2750. Die Untersuchung von 16 Elternpaaren mit ihren 21 Kindern ergab keine Abweichung vom angenommenen autosomal kodominanten Erbgang.

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References

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Umetsu, K., Kashimura, S., Ikeda, N. et al. Classification ofα 2-HS-glycoprotein (α 2HS) types by isoelectric focusing. Z Rechtsmed 91, 33–35 (1983). https://doi.org/10.1007/BF01882446

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  • DOI: https://doi.org/10.1007/BF01882446

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