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Oxidative metabolism in a teleost,Anabas testudineus Bloch: effect of testosterone and estradiol-17β on hepatic enzyme activities

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Abstract

Testosterone (T) administration to maleAnabas testudineus significantly stimulated the activities of cytochrome oxidase, α-glycerophosphate dehydrogenase (α-GPDH) and Mg2+ adenosine triphosphatase (Mg2+ ATPase) and inhibited lactate dehydrogenase (LDH), cytosolic and mitochondrial malate dehydrogenases (MDH). The activities of succinate dehydrogenase (SDH), glucose-6-phosphate dehydrogenase (G-6-PDH) and catalase were unaffected by testosterone treatment. Administration of estradiol-17β (E2) in female fish, significantly stimulated cytochrome oxidase activity, inhibited Mg2+ ATPase, SDH, catalase and cytosolic and mitochondrial MDH activity, and was without effect on other enzymes studied.

The simultaneous injections of actinomycin D or chloramphenicol and T or E2 prevented the hormonal influence on hepatic enzyme activities. The present study demonstrates that inA. testudineus sex steroids influence hepatic oxidative metabolism by a mechanism sensitive to the action of inhibitors of protein synthesis.

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  1. Department of Zoology, University of Kerala, Kariavattom, 695 581, Trivandrum, India

    M. C. Subash Peter & Oommen V. Oommen

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Subash Peter, M.C., Oommen, O.V. Oxidative metabolism in a teleost,Anabas testudineus Bloch: effect of testosterone and estradiol-17β on hepatic enzyme activities. Fish Physiol Biochem 6, 377–385 (1989). https://doi.org/10.1007/BF01875607

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