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Evaluation of vesico-urethral and sweating function in disorders presenting with parkinsonism

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Abstract

Investigation of vesico-urethral and sweating function was performed in twelve patients with classical idiopathic Parkinson's disease and ten patients with parkinsonism associated with features suggestive of more extensive involvement of the nervous system, as in the Shy—Drager syndrome. The urodynamic studies revealed detrusor hyperreflexia with reduction of maximal cystometric capacity in only one patient with Parkinson's disease (8%), but in nine patients with parkinsonism associated with other features (90%). Urethral sphincter electromyography did not indicate denervation in any patient of either group. Delayed or incomplete relaxation of the urethral sphincter during micturition was observed in seven patients with Parkinson's disease (58%) and in two patients of the other group (20%). Decreased sweating responses were found in both groups of patients when compared with control subjects. Hypohidrosis was more pronounced in parkinsonism associated with other features than in Parkinson's disease. Differences in sweating between the two sides of the body were observed in both groups of patients. Although there are differences in vesico-urethral and sweating function, they do not precisely differentiate between patients with classical Parkinson's disease and those with parkinsonism associated with features suggestive of more extensive involvement of the nervous system.

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References

  1. Appenzeller O, Goss JE. Autonomic deficits in Parkinson's syndrome.Arch Neurol 1971;24: 50–57.

    PubMed  Google Scholar 

  2. Takahashi A. Autonomic nervous system disorders in Parkinson's disease.Eur Neurol 1991;31 (suppl 1): 41–47.

    Google Scholar 

  3. Singer C, Weiner WJ, Sanchez-Ramos JR. Autonomic dysfunction in men with Parkinson's disease.Eur Neurol 1992;32: 134–140.

    PubMed  Google Scholar 

  4. Shy GM, Drager GA. A neurological syndrome associated with orthostatic hypotension.Arch Neurol 1960;2: 511–527.

    PubMed  Google Scholar 

  5. Khurana RK, Nelson E, Azzarelli B, Garcia JH. Shy—Drager syndrome: diagnosis and treatment of cholinergic dysfunction.Neurology 1980;30: 805–809.

    PubMed  Google Scholar 

  6. Bannister R, Mathias CJ. Clinical features and investigation of the primary autonomic failure syndromes. In: Bannister R, Mathias CJ, eds.Autonomic Failure. A Textbook of Clinical Disorders of the Autonomic Nervous System. Third edition. Oxford: Oxford University Press, 1992: 531–547.

    Google Scholar 

  7. Aranda B, Perrigot M, Mazières L, Pierrot-Deseilligny E. Les troubles vésico-sphinctériens de la maladie de Parkinson.Rev Neurol 1983;139: 283–288.

    PubMed  Google Scholar 

  8. Galloway NTM. Urethral sphincter abnormalities in parkinsonism.Br J Urol 1983;55: 691–693.

    PubMed  Google Scholar 

  9. Fitzmaurice H, Fowler CJ, Rickards D, Kirby RS, Quinn NP, Marsden CD, Milroy EJG, Turner-Warwick RT. Micturition disturbance in Parkinson's disease.Br J Urol 1985;57: 652–656.

    PubMed  Google Scholar 

  10. Berger Y, Blaivas JG, De La Rocha ER, Salinas JM. Urodynamic findings in Parkinson's disease.J Urol 1987;138: 836–838.

    PubMed  Google Scholar 

  11. Khan Z, Starer P, Bhola A. Urinary incontinence in female Parkinson disease patients.Urology 1989;33: 486–489.

    PubMed  Google Scholar 

  12. Kirby RS, Bannister R. Bladder dysfunction in progressive autonomic failure.Br Med J 1986;293: 223–224.

    Google Scholar 

  13. Salinas JM, Berger Y, De La Rocha RE, Blaivas JG. Urological evaluation in the Shy—Drager syndrome.J Urol 1986;135: 741–743.

    PubMed  Google Scholar 

  14. Kirby R, Fowler C, Gosling J, Bannister R. Urethro-vesical dysfunction in progressive autonomic failure with multiple system atrophy.J Neurol Neurosurg Psychiatry 1986;49: 554–562.

    PubMed  Google Scholar 

  15. Masson C. Dysatonomie et atrophie multisystématisée du système nerveux (syndrome de Shy—Drager).Presse Méd 1992;21: 619–624.

    Google Scholar 

  16. Lewin RJ, Dillard GV, Porter RW. Extrapyramidal inhibition of the urinary bladder.Brain Res 1967;4: 301–307.

    PubMed  Google Scholar 

  17. Berger Y, Salinas JN, Blaivas JG. Urodynamic differentiation of Parkinson's disease and the Shy—Drager syndrome.Neurourol Urodynam 1990;9: 117–121.

    Google Scholar 

  18. Sung JH, Mastri AR, Segal E. Pathology of the Shy—Drager syndrome.J Neuropathol Exp Neurol 1978;38: 253–268.

    Google Scholar 

  19. Konno H, Yamamoto T, Iwasaki Y, Iizuka H. Shy—Drager syndrome and amyotrophic lateral sclerosis.J Neurol Sci 1986;73: 193–204.

    PubMed  Google Scholar 

  20. Eardley I, Quinn NP, Fowler CJ, Kirby RS, Parkhouse HF, Marsden CD, Bannister R. The value of urethral sphincter electromyography in the differential diagnosis of parkinsonism.Br J Urol 1989;64: 360–362.

    PubMed  Google Scholar 

  21. Goetz CG, Lutge W, Tanner CM. Autonomic dysfunction in Parkinson's disease.Neurology 1986;36: 73–75.

    PubMed  Google Scholar 

  22. Turkka JT, Myllyla VV. Sweating dysfunction in Parkinson's disease.Eur Neurol 1987;26: 1–7.

    Google Scholar 

  23. De Marinis M, Stocchi F, Testa SR, De Pandis F, Agnoli A. Sweating alterations in Parkinson's disease. In: Agnoli A, Fabbrini G, Stocchi F, eds.Parkinson's Disease and Extrapyramidal Disorders. Pathophysiology and Treatment. London, Rome; John Libbey-CIC, 1991: 489–493.

    Google Scholar 

  24. De Marinis M, Stocchi F, Testa SR, De Pandis F, Agnoli A. Alterations of thermoregulation in Parkinson's disease.Funct Neurol 1991;6: 279–283.

    PubMed  Google Scholar 

  25. Rosecan M, Glaser RJ, Goldman ML. Orthostatic hypotension, anhidrosis and impotence.Circulation 1952;6: 30–40.

    PubMed  Google Scholar 

  26. Cohen J, Low P, Fealey R, Sheps S, Jiang N-S. Somatic and autonomic function in progressive autonomic failure and multiple system atrophy.Ann Neurol 1987;22: 692–699.

    PubMed  Google Scholar 

  27. Minor V. Ein neues verfahren zu der klinischen untersuchung der schweiss-absonderung.Dtsch Z Nervenh 1927;101: 302–308.

    Google Scholar 

  28. Pavlakis AJ, Siroky MB, Goldstein I, Krane RJ. Neurourologic findings in Parkinson's disease.J Urol 1983;129: 80–83.

    PubMed  Google Scholar 

  29. Murnaghan GF. Neurogenic disorders of the bladder in parkinsonism.Br J Urol 1961;33: 403–409.

    PubMed  Google Scholar 

  30. Sakuta MS, Nakanishi T, Toyakuru M. Anal muscle electromyograms differ in amyotrophic lateral sclerosis and the Shy—Drager syndrome.Neurology 1978;28: 1289–1293.

    PubMed  Google Scholar 

  31. Christmas TJ, Kempster PA, Chapple CR, Frankel JP, Lees AJ, Stern GM. Role of subcutaneous apomorphine in parkinsonian voiding dysfunction.Lancet 1988;ii: 1451–1453.

    Google Scholar 

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Authors and Affiliations

  1. Department of Urology "La Sapienza" University, Rome, Italy

    Antonio Carbone & Giulio Baffigo

  2. Department of Neurological Sciences, Rome, Italy

    Milena De Marinis, Guido Argenta, Domenico Mele, Antonio Carbone, Giulio Baffigo & Alessandro Agnoli

Authors
  1. Milena De Marinis
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  2. Guido Argenta
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  3. Domenico Mele
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  4. Antonio Carbone
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  5. Giulio Baffigo
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  6. Alessandro Agnoli
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De Marinis, M., Argenta, G., Mele, D. et al. Evaluation of vesico-urethral and sweating function in disorders presenting with parkinsonism. Clinical Autonomic Research 3, 125–130 (1993). https://doi.org/10.1007/BF01818997

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  • DOI: https://doi.org/10.1007/BF01818997

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