Abstract
The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5 M trimetaphosphate in alkaline solution gives a mixture of 2- and 3-phosphoglyceric acids in combined yields of up to 40%.
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Abbreviations
- P3!:
-
trimetaphosphate
- 2-P:
-
2-Phosphoglycerate
- 3-P:
-
3-Phosphoglycerate
- TSPS:
-
3-trimethylsilyl propionic acid, sodium salt
- NMR:
-
nuclear magnetic resonance
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Kolb, V., Orgel, L.E. Phosphorylation of glyceric acid in aqueous solution using trimetaphosphate. Origins Life Evol Biosphere 26, 7–13 (1996). https://doi.org/10.1007/BF01808156
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DOI: https://doi.org/10.1007/BF01808156