Summary
204 placental samples from a German population were screened for variants of mitochondrial glutamic oxalo-acetic transaminase. Three variants were found occurring at a frequency of 1.47%. This is comparable with frequencies reported in other Caucasian populations. No variants of the soluble form were found.
Zusammenfassung
204 Placentaproben einer deutschen Stichprobe wurden auf Varianten der Mitochondrien-Glutamat-Oxalat-Transaminase (M-GOT) untersucht. Drei Varianten wurden gefunden, was einer Häufigkeit von 1,47% entspricht. Dieser Wert steht im Einklang mit den Ergebnissen von Untersuchungen anderer europider Populationen. Varianten der löslichen Form (S-GOT) konnten nicht gefunden werden.
References
Chen, S. H., Giblett, E. R.: Genetic variation of soluble glutamic oxalo-acetic transaminase in man. Amer. J. hum. Genet.23, 419–424 (1971).
Davidson, R. G., Cortner, J. A., Rattazzi, M. C., Ruddle, F. H., Lubs, H. A.: Genetic polymorphisms of human mitochondrial glutamic oxaloacetic transaminase. Science169, 391–392 (1970).
Hackel, E., Hopkinson, D. A., Harris, H.: Population studies on mitochondrial glutamate oxaloacetate transaminase. Ann. hum. Genet.35, 491–496 (1972).
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Alexander von Humboldt Fellow.
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Ananthakrishnan, R., Beck, W. & Walter, H. Polymorphism of mitochondrial glutamic oxalo-acetic transaminase in a German population. Hum Genet 17, 89–90 (1972). https://doi.org/10.1007/BF01789608
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DOI: https://doi.org/10.1007/BF01789608