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Study of the intraosseous vessels of the femoral head in patients with fractures of the femoral neck or osteoarthritis of the hip

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Abstract

Bearing in mind earlier studies which established a link between arteriosclerosis and mineral loss, or fragility of the bones, and also our recent study showing that patients with arterial disorders of the lower limbs also suffered from osteoporosis, we carried out a histological study of the number and appearance of the intraosseous vessels and trabecular bone volume in the femoral heads of patients undergoing surgery for either fracture of the femoral neck or osteoarthritis of the hip. The number of thick-walled vessels, arterioles or arterial capillaries was significantly diminished in the femoral heads of patients with fractures of the femoral neck (p=0.007). In addition, in the latter patients, arteriosclerotic vascular lesions (rupture of the internal elastic lamina, medial thickening and fibrosis) were more frequent than in patients with osteoarthritis of hip. The possibility that, through chronic ischemia, arteriosclerosis may lead to disturbance of bone remodelling and loss of the mechanical properties of bone has not been contradicted by these findings.

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Authors and Affiliations

  1. Service d'Anatomo-Pathologie, CHU Rangueil, Toulouse, France

    M. Pieraggi

  2. Service d'Orthopédie et Traumatologie, CHU Rangueil, Toulouse, France

    P. Chiron, J. Puget & G. Utheza

  3. Service de Rhumatologie, CHU Rangueil, 1 avenue Jean-Poulhès, F-31054, Toulouse Cedex, France

    M. Laroche, I. Ludot, M. Thiechart, J. Arlet, L. Moulinier, A. Cantagrel & B. Mazières

Authors
  1. M. Laroche
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  2. I. Ludot
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  3. M. Thiechart
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  4. J. Arlet
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  5. M. Pieraggi
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  6. P. Chiron
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  7. L. Moulinier
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  8. A. Cantagrel
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  9. J. Puget
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  10. G. Utheza
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  11. B. Mazières
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Laroche, M., Ludot, I., Thiechart, M. et al. Study of the intraosseous vessels of the femoral head in patients with fractures of the femoral neck or osteoarthritis of the hip. Osteoporosis Int 5, 213–217 (1995). https://doi.org/10.1007/BF01774009

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  • DOI: https://doi.org/10.1007/BF01774009

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