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Shunt nephritis associated withPropionibacterium acnes

Shuntnephritis mit Propionibacterium acnes

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Summary

Membranoproliferative glomerulonephritis was observed in a 22-year-old male patient in whom a ventriculoatrial shunt and a ventricular catheter were implanted after he was diagnosed in September 1989 with a cerebral cyst.Propionibacterium acnes infection of a central nervous system shunt was diagnosed. The venticuloatrial shunt was removed (the catheter had become embedded in tissue and was left in place) and the patient was treated with cefotaxime (3×2 g) for 14 days. Renal function improved, but recovery was not complete.

Zusammenfassung

Bei einem 22jährigen Patienten, der im September 1989 einen ventrikuloatrialen Shunt und einen Ventrikelkatheter zur Therapie einer zerebralen Zyste implantiert erhielt, wurde eine membranoproliferative Glomerulonephritits in Assoziation mit einer Shuntinfektion durchPropionibacterium acnes diagnostiziert. Obgleich Infektionen von zentralnervösen Shunts nichts Ungewöhnliches darstellen, ist die Entwicklung einer Glomerulonephritis eine Seltenheit. Vermutlich ist die Shuntnephritis die Folge einer Immunkomplexantwort und der Ablagerung von Immunkomplexen in der Niere. Nach der nur unvollständigen Entfernung des Shunts aufgrund technischer Probleme und zusätzlicher Gabe von 3 × 2 g Cefotaxim für 14 Tage verbesserte sich die Nierenfunktion, jedoch trat keine komplette Remission ein.

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References

  1. Brook, I., Frazier, E. H. Anaerobic osteomyelitis and arthritis in a military hospital; a 10-year experience. Am. J. Med. 94 (1993) 21–28.

    Google Scholar 

  2. Frank, J. A., Friedman, H. S., Davidson, D. M., Falletta, J. M., Kinney, T. R. Propionibacterium shunt nephritis in two adolescents with medulloblastoma. Cancer 52 (1983) 330–333.

    Google Scholar 

  3. Groeneveld, A. B. J., Nommensen, F. E., Mullink, H., Ooms, E. C. M., Bode, W. A. Shunt nephritis associated withPropionibacterium acnes with demonstration of the antigen in the glomeruli. Nephron 32 (1982) 365–369.

    Google Scholar 

  4. Skinner, P. R., Taylor, A. J., Coakham, H. Propionibacteria as a cause of shunt and postneurosurgical infections. J. Clin. Pathol. 51 (1978) 1085–1090.

    Google Scholar 

  5. Beeler, B. A., Crowder, J. G., Smith, J.W., White, A. Propionibacterium acnes: pathogen in central nervous system shunt nephritis. Am. J. Med. 61 (1976) 935–938.

    Google Scholar 

  6. Finney, H. L., Roberts, T. S. Nephritis secondary to chronic cerebrospinal fluid — vascular shunt infection: “shunt nephritis”. Child's Brain 6 (1980) 169–193.

    Google Scholar 

  7. Everett, E. D., Eickhoff, T. C., Simon, R. H. Cerebrospinal fluid shunt infections with anaerobic diphtheroids (Propionibacterium species). J. Neurosung. 44 (1976) 580–584.

    Google Scholar 

  8. Noble, R. C., Overman, S. B. Propionibacterium acnes osteomyelitis: case report and review of the literature. J. Clin. Microbiol. 25 (1987) 251–254.

    Google Scholar 

  9. Lewis, J. F., Abramson, J. H. Endocarditis due toPropionibacterium acnes. Am. J. Clin. Pathol. 74 (1980) 690–696.

    Google Scholar 

  10. Felner, J. M., Dowell, J. R. Anaerobic bacterial endocarditis. N. Engl. J. Med. 283 (1970) 1188–1192.

    Google Scholar 

  11. Black, J. A., Challacombe, D. N. Nephrotic syndrome associated with bacteraemia after operations for hydrocephalus. Lancet ii (1965) 921–924.

    Google Scholar 

  12. Stauffer, U. G., Csomor, A., Plüss, H. L., Hitzig, W. H. Diffuse Glomerulonephritis infolge infizierter ventriculo-atrialer Shunts. Schweiz. med. Wochenschr. 100 (1970) 1288–1291.

    Google Scholar 

  13. Stauffer, U. G. “Shunt nephritis”: diffuse glomerulonephritis complicating ventriculo-atrial shunts. Devl. Med. Child. Neur. 12 Suppl. 22 (1970) 161–164.

    Google Scholar 

  14. Dobrin, R. S., Day, N. K., Quie, P. G., Moore, H. L., Vernier, R. L., Michael, A. F., Fish, A. J. The role of complement, immunoglobulin and bacterial antigen in coagulase-negative staphylococcal shunt nephritis. Am. J. Med. 59 (1975) 660–673.

    Google Scholar 

  15. Bolton, W. K., Sande, M. A., Normansell, D. E., Sturgill, B. C., Westervelt, F. B. Ventriculojugular shunt nephritis withCorynebacterium bovis. Am. J. Med. 59 (1975) 417–423.

    Google Scholar 

  16. Kaufmann, D. B., McIntosh, R. The pathogenesis of the renal lesion in a patient with streptoccocal disease, infected ventriculoatrial shunt, cryoglobulinemia and nephritis. Am. J. Med. 50 (1971) 262–268.

    Google Scholar 

  17. O'Regan, S., Makker, S. P. Shunt nephritis: demonstration of diphtheroid antigen in glomeruli. Am. J. Med. Sci. 278 (1979) 161–165.

    Google Scholar 

  18. Schoenbaum, S. C., Gardner, P., Shilito, J. Infections of cerebrospinal fluid shunts: epidemiology, clinical manifestations and therapy. J. Infect. Dis. 131 (1975) 543–553.

    Google Scholar 

  19. McLaurin, R. L. Infected cerebrospinal shunts. Surg. Neurol. 1 (1973) 191–195.

    Google Scholar 

  20. Forrest, D. M., Cooper, G. W. Complications of ventriculoatrial shunts: a review of 455 cases. J. Neurosurg. 29 (1968) 506–512.

    Google Scholar 

  21. Bayston, R., Swinden, J. The etiology and prevention of shunt nephritis. Z. Kinderchir. 28 (1979) 377–384.

    Google Scholar 

  22. Narchi, H., Taylor, R., Azmy, A. F., Murphy, A. V., Beattie, T. J. Shunt nephritis. J. Paediatr. Surg. 23 (1988) 839–841.

    Google Scholar 

  23. Arze, R. S., Rashid, H., Morley, R., Ward, M. K., Kerr, D. N. S. Shunt nephritis; report of two cases and review of the literature. Clin. Nephrol. 19 (1983) 48–53.

    Google Scholar 

  24. Wakabayashi, Y., Kobayashi, Y., Shigematsu, H. Shunt nephritis: histological dynamics following removal of the shunt. Nephron 40 (1985) 111–117.

    Google Scholar 

  25. Levy, M., Gubler, M. C., Habib, R.: Pathology and immunopathology of shunt nephritis in children: report of 10 cases. In: Proc. 8th Int. Congr. Nephrol., Athens, 1981, pp 291–296.

  26. Stickler, G. B., Shin, M. H., Burke, E. C., Holley, K. E., Miller, R. H., Segar, W. E. Diffuse glomerulonephritis associated with infected ventriculo-atrial shunt. N. Engl. J. Med. 279 (1968) 1077–1082.

    Google Scholar 

  27. Moss, S. W., Gary, N. E., Eisinger, R. P. Nephritis associated with a diphtheroid-infected cerebrospinal fluid shunt. Am. J. Med. 63 (1977) 318–319.

    Google Scholar 

  28. Strife, C. F., McDonald, B. M., Ruley, E. F., McAdams, A. J., West, C. D. Shunt nephritis: the nature of the serum cryoglobulins and their relation to the complement profile. J. Pediatr. 88 (1976) 403–413.

    Google Scholar 

  29. Caron, C., Luneau, C., Gervais, M. H., Plante, G. E., Sanchez, G., Blain, G. La glomérulonéphrite de shunt: manifestations cliniques et histopathologiques. Can. Med. Ass. J. 120 (1979) 557.

    Google Scholar 

  30. Pierre-Kahn, A., Labrune, B., Levy, M., Dufour, G., Hirsch, J. F. Glomérulonéphrites des dérivations ventriculo-atriales. Neuro-Chirurgie 19 (1973) 387–398.

    Google Scholar 

  31. Shurtleff, D. B., Foltz, E. L., Weeks, R. D., Loeser, J. Therapy ofStaphylococcus epidermidis: infections associated with cerebrospinal fluid shunts. Pediatrics 53 (1974) 55–62.

    Google Scholar 

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Authors and Affiliations

  1. Institut für Umweltmedizin und Krankenhaushygiene, Universität Freiburg, Hugstetterstr. 55, D-79106, Freiburg, Germany

    Ulrike Setz,  U. Frank,  K. Anding M. D. &  F. D. Daschner

  2. Medizinische Klinik, Universität Freiburg, Hugstetterstr. 55, D-79106, Freiburg, Germany

    A. Garbe M. D.

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  1. Ulrike Setz
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  2. U. Frank
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  4. F. D. Daschner
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  5. A. Garbe M. D.
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Setz, U., Frank, U., Anding, K. et al. Shunt nephritis associated withPropionibacterium acnes . Infection 22, 99–101 (1994). https://doi.org/10.1007/BF01739014

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  • DOI: https://doi.org/10.1007/BF01739014

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