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Sequence analysis of pre-S/S gene of hepatitis B virus strains of genotypes A, D, and F isolated in Brazil

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Summary

The nucleotide sequences of pre-S/S gene of nine hepatitis B virus strains (3adw2, 3ayw2, and 3ayw3) and of pre-S region of twoadw4 isolates from Rio de Janeiro, Brazil, were determined. Phylogenetic analysis allowed to classify these strains into three genotypes, A, D and F, reflecting the diverse origin of the population. However, strains belonging to a same genotype were separated by a short evolutionary distance. The presence of aminoacid mutations into pre-S region not found in hepatitis B viruses isolated in other parts of the world is described.

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Authors and Affiliations

  1. Department of Virology, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil

    M. T. B. Moraes, S. A. Gomes & C. Niel

Authors
  1. M. T. B. Moraes
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  2. S. A. Gomes
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  3. C. Niel
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Additional information

The sequences reported in this paper have been submitted to Genbank and assigned accession numbers U55220-U55230.

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Moraes, M.T.B., Gomes, S.A. & Niel, C. Sequence analysis of pre-S/S gene of hepatitis B virus strains of genotypes A, D, and F isolated in Brazil. Archives of Virology 141, 1767–1773 (1996). https://doi.org/10.1007/BF01718299

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  • DOI: https://doi.org/10.1007/BF01718299

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