Skip to main content
Log in

Heparin-induced thrombocytopaenia complicated by bilateral adrenal haemorrhage

  • Case Reports
  • Published:
Intensive Care Medicine Aims and scope Submit manuscript

Abstract

Acute adrenal insufficiency due to bilateral adrenal haemorrhage is an important clinical diagnosis and its association with heparin-induced thrombocytopaenia is infrequent. We report on a patient in whom life threatening acute adrenal insufficiency occurred consequent to such an association. The clinical manifestations simulated septic shock, highlighting the need to consider specifically acute adrenal insufficiency in such settings, and institute therapy promptly prior to obtaining results of confirmatory tests.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Gallus AG, Goodall KT, Beswick W, Chesterman CN (1980) Heparin-associated thrombocytopaenia: case report and prospective study. Aust NZ J Med 10:25–31

    Google Scholar 

  2. Warkentin TE, Kelton JG (1989) Heparin-induced thrombocytopaenia. Am Rev Med 40:31–44

    Google Scholar 

  3. King DJ, Kelton JG (1984) Heparin-associated thrombocytopaenia. Ann Intern Med 100:535–540

    PubMed  Google Scholar 

  4. Arthur CK, Grant SJB, Murray WK, Isbister JP, Stiel JN, Lauer CS (1985) Heparin-associated acute adrenal insufficiency. Aust NZ J Med 15:454–455

    Google Scholar 

  5. Findling JW, Korducki JM, Lahiri PK, Muller DD, Raff H (1987) Bilateral adrenal haemorrhage associated with heparin-induced thrombocytopaenia. Wis Med J 86:27–29

    Google Scholar 

  6. Winternitz WW (1983) Adrenal haemorrhage complicating anticoagulant therapy. South Med J 76:1369–1371

    PubMed  Google Scholar 

  7. Xarli VP, Steele AA, Davis PJ, Buescher ES, Rios CN, Garcia-Bunuel R (1978) Adrenal haemorrhage in the adult. Medicine 57:211–221

    PubMed  Google Scholar 

  8. Rao RH, Vagmucci AH, Amico JA (1989) Bilateral massive adrenal haemorrhage: early recognition and treatment. Ann Intern Med 110:227–235

    PubMed  Google Scholar 

  9. Sibbald WJ, Short A, Cohen M, Wilson R (1977) Variations in adrenocortical responsiveness during severe bacterial infections. Ann Surg 186:29–33

    PubMed  Google Scholar 

  10. Drucker D, Shandling M (1985) Variable adrenocortical function in acute medical illness. Crit Care Med 13:477–479

    PubMed  Google Scholar 

  11. Dorin RI, Kearns PJ (1988) High output circulatory failure in acute adrenal insufficiency. Crit Care Med 16:296–297

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ernest, D., Fisher, M.M. Heparin-induced thrombocytopaenia complicated by bilateral adrenal haemorrhage. Intensive Care Med 17, 238–240 (1991). https://doi.org/10.1007/BF01709885

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01709885

Key words

Navigation