Abstract
Acute adrenal insufficiency due to bilateral adrenal haemorrhage is an important clinical diagnosis and its association with heparin-induced thrombocytopaenia is infrequent. We report on a patient in whom life threatening acute adrenal insufficiency occurred consequent to such an association. The clinical manifestations simulated septic shock, highlighting the need to consider specifically acute adrenal insufficiency in such settings, and institute therapy promptly prior to obtaining results of confirmatory tests.
Similar content being viewed by others
References
Gallus AG, Goodall KT, Beswick W, Chesterman CN (1980) Heparin-associated thrombocytopaenia: case report and prospective study. Aust NZ J Med 10:25–31
Warkentin TE, Kelton JG (1989) Heparin-induced thrombocytopaenia. Am Rev Med 40:31–44
King DJ, Kelton JG (1984) Heparin-associated thrombocytopaenia. Ann Intern Med 100:535–540
Arthur CK, Grant SJB, Murray WK, Isbister JP, Stiel JN, Lauer CS (1985) Heparin-associated acute adrenal insufficiency. Aust NZ J Med 15:454–455
Findling JW, Korducki JM, Lahiri PK, Muller DD, Raff H (1987) Bilateral adrenal haemorrhage associated with heparin-induced thrombocytopaenia. Wis Med J 86:27–29
Winternitz WW (1983) Adrenal haemorrhage complicating anticoagulant therapy. South Med J 76:1369–1371
Xarli VP, Steele AA, Davis PJ, Buescher ES, Rios CN, Garcia-Bunuel R (1978) Adrenal haemorrhage in the adult. Medicine 57:211–221
Rao RH, Vagmucci AH, Amico JA (1989) Bilateral massive adrenal haemorrhage: early recognition and treatment. Ann Intern Med 110:227–235
Sibbald WJ, Short A, Cohen M, Wilson R (1977) Variations in adrenocortical responsiveness during severe bacterial infections. Ann Surg 186:29–33
Drucker D, Shandling M (1985) Variable adrenocortical function in acute medical illness. Crit Care Med 13:477–479
Dorin RI, Kearns PJ (1988) High output circulatory failure in acute adrenal insufficiency. Crit Care Med 16:296–297
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ernest, D., Fisher, M.M. Heparin-induced thrombocytopaenia complicated by bilateral adrenal haemorrhage. Intensive Care Med 17, 238–240 (1991). https://doi.org/10.1007/BF01709885
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF01709885