Skip to main content
SpringerLink
Log in

A 26-year-old man with Hodgkin's disease and rapidly progressive pancytopenia

  • Clinicopathologic Conference
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Armitage JO, Bierman PJ, Vose JM, Anderson JR, Weisenburger DD, Kessinger A, Reed EC, Vaughan WP, Coccia PF, Purtilo DT (1991) Autologous bone marrow transplantation for patients with relapsed Hodgkin's disease. Am J Med 91:605–611

    Google Scholar 

  2. Bodley Scott R, Robb-Smith AHT (1939) Histiocytic medullary reticulosis. Lancet 2:194

    Google Scholar 

  3. Borg-Grech A, Radford JA, Crowther D, Swindell R, Harris M (1989) A comparative study of the nodular and diffuse variants of lymphocyte-predominant Hodgkin's disease. J Clin Oncol 7:1303–1309

    Google Scholar 

  4. Cohen JI (1991) Epstein-Barr virus lymphoproliferative disease associated with acquired immunodeficiency. Medicine (Baltimore) 70:137–160

    Google Scholar 

  5. Craig FE, Clare CN, Sklar JL, Banks PM (1992) T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol 97:189–194

    Google Scholar 

  6. Delabie J, Vandenberghe E, Kennes C, Verhoef G, Foschini MP, Stul M, Cassiman JJ, De Wolf-Peeters C (1992) Histiocyte-rich B-cell lymphoma: a distinct clinicopathologic entity possibly related to lymphocyte-predominant Hodgkin's disease, paragranuloma subtype. Am J Surg Pathol 16:37–48

    Google Scholar 

  7. Falini B, Pileri S, De Solàs I, Martelli MF, Mason DY, Delsol G, Gatter KC, Fagioli M (1990) Peripheral T-cell lymphoma associated with hemophagocytic syndrome. Blood 75:434–444

    Google Scholar 

  8. Hansmann ML, Stein H, Fellbaum C, Hui PF, Parwaresch MR, Lennert K (1989) Nodular paragranuloma can transform into high-grade malignant lymphoma of B type. Hum Pathol 20:1169–1175

    Google Scholar 

  9. Henry-Amar M, Somers R (1990) Survival outcome after Hodgkin's disease: a report from the International Data Base on Hodgkin's disease. Semin Oncol 17:758–768

    Google Scholar 

  10. Henter JI, Elinder G, Öst Å, the FHL Study Group of the Histiocyte Society (1991) Diagnostic guidelines for hemophagocytic lymphohistiocytosis. Semin Oncol 18:29–33

    Google Scholar 

  11. Herbst H, Dallenbach F, Hummel M, Niedobitek G, Pileri S, Müller-Lantzsch N, Stein H (1991) Epstein-Barr virus latent membrane protein expression in Hodgkin and Reed-Sternberg cells. Proc Natl Acad Sci USA 88:4766–4770

    Google Scholar 

  12. Jaffe ES (1988) Histiocytoses of lymph nodes: biology and differential diagnosis. Semin Diagn Pathol 5:376–390

    Google Scholar 

  13. Kadin ME, Glatstein E, Dorfman RF (1971) Clinicopathologic studies in 177 untreated patients subjected to laparotomy for the staging of Hodgkin's disease. Cancer 27:1277–1294

    Google Scholar 

  14. Kadin ME, Kamoun M, Lamberg J (1981) Erythrophagocytic T-gamma lymphoma. A clinicopathologic entity resembling malignant histiocytosis. N Engl J Med 304:648–653

    Google Scholar 

  15. Kaplan HS (1980) Pathology. In: Kaplan HS (ed) Hodgkin's Disease, 2nd edn. Harvard University Press, Cambridge, pp 53–115

    Google Scholar 

  16. Kaplan HS (1980) Clinical evaluation. In: Kaplan HS (ed) Hodgkin's disease, 2nd edn. Harvard University Press, Cambridge, pp 117–145

    Google Scholar 

  17. Kaplan HS (1980) Patterns of anatomic distribution. In: Kaplan HS (ed) Hodgkin's disease, 2nd edn. Harvard University Press, Cambridge, pp 280–339

    Google Scholar 

  18. Kaplan HS (1980) Prognosis. In: Kaplan HS (ed) Hodgkin's disease, 2nd edn. Harvard University Press, Cambridge, pp 548–597

    Google Scholar 

  19. Kim HD, Hendrickson MR, Dorfman RF (1977) Composite lymphoma. Cancer 40:959–976

    Google Scholar 

  20. Klein G (1992) Epstein-Barr virus-carrying cells in Hodgkin's disease. Blood 80; 299–301

    Google Scholar 

  21. Klimo P, Connors JM (1988) An update on the Vancouver experience in the management of advanced Hodgkin's disease treated with the MOPP/ABV hybrid program. Semin Hematol 25 [Suppl 2]: 34–40

    Google Scholar 

  22. Kluin-Nelemans JC, Noordijk EM (1990) Editorial: Staging of patients with Hodgkin's disease: what should be done? Leukemia 4:132–135

    Google Scholar 

  23. Korman LY, Smith JR, Landaw SA, Davey FR (1979) Hodgkin's disease: intramedullary phagocytosis with pancytopenia. Ann Intern Med 91:60–61

    Google Scholar 

  24. Lennert K, Hansmann ML (1978) Progressive transformation of germinal centers: clinical significance and lymphocytic predominance Hodgkin's disease: the Kiel experience. Am J Surg Pathol 11:149–150

    Google Scholar 

  25. Loy TS, Diaz-Arias AA, Perry MC (1991) Familial erythrophagocytic lymphohistiocytosis. Semin Oncol 18:34–38

    Google Scholar 

  26. Lukes RJ, Butler JJ (1966) The pathology and nomenclature of Hodgkin's disease. Cancer Res 26:1063–1083

    Google Scholar 

  27. Lukes RJ, Collins RD (1992) Tumors of the hematopoietic system. AFIP, Washington

    Google Scholar 

  28. Lukes RJ, Craver LF, Hall TC, Rappaport H, Ruben P (1966) Report on the momenclature committee. Cancer Res 26:1311

    Google Scholar 

  29. Miettinen M, Franssila KO, Saxen E (1983) Hodgkin's disease, lymphocytic predominance nodular. Increased risk for subsequent non-Hodgkin's lymphomas. Cancer 51:2293–2300

    Google Scholar 

  30. Moran EM, Ultmann JE (1974) Clinical features and course of Hodgkin's disease. In: Rosenberg SA (ed) Hodgkin's disease and other lymphomas. Saunders, London, pp 91–129

    Google Scholar 

  31. Nalesnik MA (1991) Lymphoproliferative disease in organ transplant recipients. Springer Semin Immunopathol. 13:199–216

    Google Scholar 

  32. Pallesen G, Hamilton-Dutoit SJ, Rowe M, Young LS (1991) Expression of Epstein-Barr virus latent gene products in tumour cells of Hodgkin's disease. Lancet 337:320–322

    Google Scholar 

  33. Press OW, Livingston R, Mortimer J, Collins C, Appelbaum F (1991) Treatment of relapsed non-Hodgkin's lymphomas with dexamethasone, high-dose cytarabine, and cisplatin before marrow transplantation. J Clin Oncol 9:423–431

    Google Scholar 

  34. Purtilo DT, Stevenson M (1991) Lymphotropic viruses as etiologic agents of lymphoma. Hematol Oncol Clin North Am 5:901–923

    Google Scholar 

  35. Reiner A, Spivak JL (1988) Hematophagic histiocytosis. A report of 23 new patients and a review of the literature. Medicine (Baltimore) 67:369–388

    Google Scholar 

  36. Reznek RH, Richards MA (1987) The radiology of lymphoma. In: McElwain TJ, Lister TA (eds) Clinical haematology: the lymphomas. Ballière Tindall, London, pp 77–107

    Google Scholar 

  37. Rijswijk REN, Sybesma JPHB, Kater L (1983) A prospective study of the changes in the immune status before, during, and after multiple-agent chemotherapy for Hodgkin's disease. Cancer 51:637–644

    Google Scholar 

  38. Risdall RJ, McKenna RW, Nesbit ME, Drivit W, Balfour HH jr, Simmons RL, Brunning RD (1979) Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44:993–1002

    Google Scholar 

  39. Rosner F, Grünwald HW (1984) Association of T-cell acute lymphoblastic leukemia and histiocytic medullary reticulosis. Am J Med 77:910–914

    Google Scholar 

  40. Somers R, Henry-Amar M, Meerwaldt JH, Carde P (1990) Treatment strategy in Hodgkin's disease, John Libbey Eurotext, London

    Google Scholar 

  41. Sundeen JT, Cossman J, Jaffe ES (1988) Lymphocyte-predominant Hodgkin's disease nodular subtype with coexistent “large cell lymphoma”. Am J Surg Pathol 12:599–606

    Google Scholar 

  42. Swerdlow SH (1992) Hodgkin's disease. In: Silverberg SG (ed) Biopsy interpretation of lymph nodes. Raven, New York, p 301

    Google Scholar 

  43. Swerdlow SH (1992) Histiocytic and other non-lymphoid proliferations. In: Silverberg SG (ed) Biopsy interpretation of lymph nodes. Raven, New York, pp 342–368

    Google Scholar 

  44. Timens W. Visser L, Poppema S (1986) Nodular lymphocyte predominance type of Hodgkin's disease is a germinal center lymphoma. Lab Invest 54:457–461

    Google Scholar 

  45. Trudel MA, Krikorian JG, Neiman RS (1987) Lymphocyte predominance Hodgkin's disease. A clinicopathologic reassessment. Cancer 59:99–106

    Google Scholar 

  46. Tucker MA, Coleman CN, Cox RS, Varghese A, Rosenberg SA (1988) Risk of second cancers after treatment for Hodgkin's disease. N Engl J Med 318:76–81

    Google Scholar 

  47. Warnke RA, Kim H, Dorfman RF (1975) Malignant histiocytosis (histiocytic medullary reticulosis). I. Clinicopathologic study of 29 cases. Cancer 35:215–230

    Google Scholar 

  48. Wilson MS, Weiss LM, Gatter KC, Mason DY, Dorfman RF, Warnke RA (1990) Malignant histiocytosis. A reassessment of cases previously reported in 1975 based on paraffin section immunophenotyping studies. Cancer 66:530–536

    Google Scholar 

  49. Zijlmans JMJM, Van Rijthoven AWAM, Kluin PhM, Jiwa NM, Dijkmans BAC, Kluin-Nelemans JC (1992) Epstein-Barr virus-associated lymphoma in a patient with rheumatoid arthritis treated with cyclosporine. N Engl J Med 326:1363–1363

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Hematology, Leiden University Hospital, The Netherlands

    J. C. Kluin-Nelemans & R. Bieger

  2. Laboratory of Pathology, Leiden University Hospital, The Netherlands

    P. M. Kluin

Authors
  1. J. C. Kluin-Nelemans
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. M. Kluin
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. R. Bieger
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kluin-Nelemans, J.C., Kluin, P.M. & Bieger, R. A 26-year-old man with Hodgkin's disease and rapidly progressive pancytopenia. Ann Hematol 67, 49–56 (1993). https://doi.org/10.1007/BF01709667

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01709667

Keywords

Search

Navigation