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Studies of possible absorption of a flame retardant from treated fabrics worn by rats and humans

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Summary

An investigation was made of the possible migration of a flame retardant, tris (2,3-dibromopropyl) phosphate (TBPP), commercially used in childrens sleepwear, to the skin of rats and humans and subsequent absorption. When the pure chemical was applied directly to the shaved skin of a rat, the hydrolysis product, 2,3-dibromopropanol (DBP), appeared in the urine. The 10,000 X g supernatant fraction of rat liver hydrolyzed TBPP to DBP. When TBPP-finished fabrics were worn by a rat, an adult male and a 5-year old boy for up to 9 days, DBP was not detected in the urine.

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Authors and Affiliations

  1. Cornell University, 14853, Ithaca, N.Y.

    L. E. St. John Jr., M. E. Eldefrawi & D. J. Lisk

  2. Pesticide Residue Laboratory, Department of Food Science, New York State College of Agriculture and Life Sciences, Cornell University, 14853, Ithaca, New York

    L. E. St. John Jr. & D. J. Lisk

  3. Section of Neurobiology and Behavior, Cornell University, 14853, Ithaca, New York

    M. E. Eldefrawi

Authors
  1. L. E. St. John Jr.
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  2. M. E. Eldefrawi
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  3. D. J. Lisk
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St. John, L.E., Eldefrawi, M.E. & Lisk, D.J. Studies of possible absorption of a flame retardant from treated fabrics worn by rats and humans. Bull. Environ. Contam. Toxicol. 15, 192–197 (1976). https://doi.org/10.1007/BF01685160

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  • DOI: https://doi.org/10.1007/BF01685160

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