Summary
210 clinical isolates of typhoid salmonellae, cultivated from blood of patients with typhoid fever (108 strains ofSalmonella typhi, 99 strains ofSalmonella paratyphi A and three strains ofSalmonella paratyphi B) as well as 266 random clinical isolates ofEscherichia coli (n=152),Klebsiella spp. (n=51) andProteus spp. (n=63) were tested for susceptibility to ofloxacin, using an agar dilution method. All the typhoid salmonellae were found to be highly sensitive to ofloxacin with MICs ranging from 0.03 mg/l to 0.12 mg/l. The sensitivity pattern of enterobacteriaceae was comparable to data published internationally.
Zusammenfassung
210 klinische Isolate vonSalmonella typhi (n=108),Salmonella paratyphi A (n=99) undSalmonella paratyphi B (n=3), die aus Blutkulturen von Typhuspatienten gezüchtet worden waren, sowie 266 unausgewählte klinische Isolate vonEscherichia coli (n=152),Klebsiella spp. (n=51) undProteus spp. (n=63) wurden mittels Agardilutionstest auf ihre Empfindlichkeit gegenüber Ofloxacin geprüft. Alle Typhus-Salmonellen erwiesen sich als hochempfindlich gegen Ofloxacin (MHK-Werte 0,03 mg/l bis 0,12 mg/l); die getesteten Enterobacteriaceae entsprachen in ihrem Empfindlichkeitsverhalten international mitgeteilten Werten.
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Hannan, A. In vitro activity of ofloxacin against 210 clinical isolates of typhoid salmonellae. Infection 14 (Suppl 4), S243–S244 (1986). https://doi.org/10.1007/BF01661282
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DOI: https://doi.org/10.1007/BF01661282