Skip to main content
SpringerLink
Log in

Surgical complications of typhoid fever: Enteric perforation

  • Published:
World Journal of Surgery Aims and scope Submit manuscript

Abstract

Typhoid fever remains a prevalent disease in developing nations as the result of adverse socioeconomic factors. The most frequent complication, and principal cause of mortality, is perforation of the terminal ileum. This report presents our experience with 96 patients surgically treated at Cayetano Heredia University Hospital in Lima, Peru from 1972 to 1986. The clinical characteristics and the diverse surgical procedures utilized in the management of these patients are reviewed.

Résumé

La fièvre typhoïde reste une maladie fréquente dans les pays en voie de développement en raison des facteurs économiques et sociaux. La principale complication et cause de mortalité est la perforation de l'iléon terminal. Ce travail rapporte notre expérience chez 96 patients traités chirurgicalement à l'hôpital Universitaire Cayétano Hérédia à Lima, Pérou, pour la période de 1972 à 1986. Les caractéristiques cliniques et les différents procédés chirurgicaux employés pour le traitement de ces patients sont passés en revue.

Resumen

La fiebre tifoidea sigue siendo una entidad clínica prevalente en las naciones en desarrollo, como expresión de factores socioeconómicos adversos. La complicación más frecuente, que también representa la mayor causa de mortalidad, es la perforación del ileon terminal. Se presenta nuestra experiencia con 96 pacientes intervenidos quirúrgicamente en el Hospital de la Universidad Cayetano Heredia de Lima, Peru, en el período 1972–1986. Se hace una revisión de las características clínicas y de los diversos procedimientos operatorios utilizados en el manejo de estos pacientes.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Gottuzo, E.: Características Epidemiológicas de la Fiebre Tifoidea y la Perforatión Intestinal. Curso de Post grado: Cirugía General. XXII Congreso Peruano de Cirugía, 1980

  2. Badejo, O.A., Arigbabu, A.O.: Operative treatment of typhoid perforation with peritoneal irrigation: A comparative study. Gut21:141, 1980

    Google Scholar 

  3. Meier, D., Obioha, O., Imediegwu, Tarpley, J.: Perforated typhoid enteritis: Operative experience with 108 cases. Am. J. Surg.157:423, 1989

    Google Scholar 

  4. Chouhan, M.K., Pande, S.K.: Typhoid enteric perforation of the intestine. Br. J. Surg.69:173, 1982

    Google Scholar 

  5. Butler, T., Knight, J., Samir, K.N., Speelman, P., Swapan, K.R., Azad, M.A.K.: Typhoid fever complicated by intestinal perforation: A persisting fatal disease requiring surgical management. Rev. Infect. Dis.7:244, 1985

    Google Scholar 

  6. Huaraz Loyola, D.: Complicaciones quirúrgicas de la fiebre tifoidea; perforatión de intestino delgado y enterorragia masiva. Actualidad Médica1:27, 1989

    Google Scholar 

  7. Kim, J.P., On, S.K., Jarret, F.: Management of ileal perforation due to typhoid fever. Ann. Surg.181:88, 1975

    Google Scholar 

  8. Eggleston, F.C., Santoshi, B.: Typhoid perforation: Choice of operation. Br. J. Surg.68:341, 1981

    Google Scholar 

  9. Vyas, J.D., Purohit, M.G., Patel, H.L.: Simultaneous typhoid ileal perforation in identical twin brothers. Br. J. Clin. Pract.34:256, 1980

    Google Scholar 

  10. Li, F.W.P.: Surgical treatment of typhoid perforation of the intestine. Br. J. Surg.50:976, 1963

    Google Scholar 

  11. Pons, P.: Enfermedades Infecciosas. Intoxicaciones, Enfermedades Profesionales y por Agentes Físicos, Barcelona, Editorial Salvat, 1960

  12. Edelman, R., Levine, M.M.: Summary of an international workshop on typhoid fever. Rev. Infect. Dis.8:329, 1986

    Google Scholar 

  13. Olobuyide, I.O., Brown, N.M., Higginson, J., Whicher, J.T.: The value of C-reactive protein in the diagnoses of intestinal perforation in typhoid fever. Ann. Clin. Biochem.26(PT3):246, 1989

    Google Scholar 

  14. Van Hook W.: Laparotomy for intestinal perforation in typhoid fever with the report of a successful case. Medical News159:591, 1891

    Google Scholar 

  15. Bitar, R., Tarpley, J.: Intestinal perforation in typhoid fever: A historical state of the art. Rev. Infect. Dis.7:257, 1985

    Google Scholar 

  16. Woodward, T.E., Smadel, J.E., Parker, R.T., Wisseman, Jr., C.L.: Treatment of typhoid fever with antibiotics. Ann. N.Y. Acad. Sci.55:1043, 1952

    Google Scholar 

  17. Huckstep, R.L.: Recent advances in the surgery of typhoid fever. Ann. R. Coll. Surg. Engl.26:207, 1960

    Google Scholar 

  18. Archampong, E.Q.: Operative treatment of the typhoid perforation of the bowel. Br. Med. J.3:273, 1969

    Google Scholar 

  19. Olurin, E.O., Ajavi, O.O., Bohrer, S.P.: Typhoid perforation. J. R. Coll. Surg. Edinb.17:264, 1972

    Google Scholar 

  20. Mulligan, T.O.: The treatment of typhoid perforation of the ileum. J. R. Coll. Edinb.17:364, 1972

    Google Scholar 

  21. Hoffman, S., Punjab, N.H., Kumala, S., Moechtar, M.A., Pulungsih, S.P., Rivai, A.R., Rockhill A.R., Rockhill, R.C., Woodward, T.E., Loeding, A.A.: Reduction of mortality in chloramphenicol treated severe typhoid fever by high-dose dexamethasone. N. Engl. J. Med.310:82, 1984

    Google Scholar 

  22. Gibney, E.J.: Typhoid perforation. Br. J. Surg.76:887, 1989

    Google Scholar 

  23. Arigon, J.B., Pillay, S.P., Hagarty, M., Baker, L.W.: Typhoid perforation of the ileum. South Afr. Med. J.49:781, 1975

    Google Scholar 

  24. Ramirez, M., Santillana, M.: Use of an elemental diet for nutritional management of severely undernourished immunocompromised patients with gastrointestinal fistulas: Experience in Peru. Nutrition4:367, 1988

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Surgery, Cayetano Heredia University School of Medicine, Lima, Peru

    Miguel Santillana M.D.

Authors
  1. Miguel Santillana M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Santillana, M. Surgical complications of typhoid fever: Enteric perforation. World J. Surg. 15, 170–175 (1991). https://doi.org/10.1007/BF01659050

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01659050

Keywords

Search

Navigation