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Wound infections in appendicitis: Effective prophylaxis

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Abstract

Wound infections following appendectomy continue to occur at a surprisingly high rate. Individual prophylactic methods have been shown to reduce the incidence but are unlikely to eliminate infections owing to the multifactorial nature of their etiology. No study in which multiple methods were used has yet been reported. In this study 100 consecutive cases of appendicitis were treated by multiple methods including good surgical technique, protective wound packs, avoidance of drains, and systemic antibiotics (penicillin, gentamicin, and clindamycin), in appendicitis associated with perforation, gangrene, or abscess formation. By using these methods a 1% wound infection rate was achieved, the lowest rate yet reported for 100 consecutive cases of appendicitis.

Résumé

L'infection pariétale secondaire à l'appendicectomie atteint encore un taux surprenant. Des méthodes prophylactiques particulières ont été prises pour le réduire mais elles ne permirent pas d'atteindre ce but en raison des multiples causes qui sont à l'origine de l'infection. Aucune étude comportant l'association de multiples moyens de prévention n'a été rapportée. L'auteur s'est donc livré à l'étude de 100 cas d'appendicite traités consécutivement en employant des moyens multiples: bonne technique chirurgicale, protection de l'incision pariétale, proscription du drainage, antibiothérapie générale (pénicilline, gentamycine, et clindamycine) pour traiter des appendicites graves: perforation, gangrène, abcès appendiculaires.

En observant ces règles, le taux de l'infection n'a pas dépassé un pour cent.

Resumen

Las infecciones de herida después de apendectomía continúan ocurriendo con una incidencia sorprendentemente elevada. Métodos profilácticos individuales han demostrado capacidad para reducir tal incidencia, pero posiblemente no serán capaces de eliminar totalmente la infección debido a la naturaleza multifactorial de su etiología.

Hasta ahora no se ha informado estudio alguno en el cual se hayan utilizado métodos múltiples.

En el presente estudio 100 casos consecutivos de apendicitis fueron tratados con métodos múltiples incluyendo: técnica quirúrgica meticulosa, proteccion de la herida con compresas, eliminación del uso de drenes y antibióticos sistémicos (penicilina, gentamicina y clindamicina) en los casos de apendicitis asociada con perforación, gangrena o absceso. Mediante el uso de estos métodos se logró una incidencia de infección de herida del 1%, la más baja que se haya informado hasta la fecha en una serie de 100 casos consecutivos de apendicitis.

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References

  1. Editorial: Sepsis after appendicectomy. Lancet 2:195, 1971

    Google Scholar 

  2. Pettigrew, R.A.: Delayed primary wound closure in gangrenous and perforated appendicitis. Br. J. Surg.68:635, 1981

    Google Scholar 

  3. Tighe, B., Anderson, M., Dodey, C., Egan, T., Domhaill, S., Delaney, P.V.: Betadine irrigation following appendicectomy. Ir. Med. J.75:96, 1982

    Google Scholar 

  4. Lau, W.Y., Fan, S.I., Yiu, T.F., Wong, S.H.: Prophylaxis of post-appendicectomy sepsis by metronidazole and ampicillin: A randomized, prospective and double-blind trial. Br. J. Surg.70:155, 1983

    Google Scholar 

  5. Longland, C.J., Gray, J.G., Lees, W., Garrett, J.A.M.: The prevention of infection in appendicectomy wounds. Br. J. Surg.58:117, 1971

    Google Scholar 

  6. Magarey, C.J., Rickford, C.R.K., Chart, A.D.B., Magarey, J.R.: Peritoneal drainage and systemic antibiotics after appendicectomy. Lancet2:179, 1971

    Google Scholar 

  7. Tanner, W.A., Ali, A.E., Collins, P.G.: Single-dose intra-rectal metronidazole as prophylaxis wound infection following emergency appendicectomy. Br. J. Surg.67:809, 1980

    Google Scholar 

  8. Donovan, T.A., Ellis, D., Gatehouse, D.: One dose antibiotic prophylaxis against wound infection after appendicectomy. Br. J. Surg.66:193, 1979

    Google Scholar 

  9. Gilmore, O.J.A., Martin, T.D.: Aetiology and prevention of wound infection in appendicectomy. Br. J. Surg.61:281, 1974

    Google Scholar 

  10. Gilmore, O.J.A., Martin, T.D., Fletcher, B.M.: Prevention of wound infection after appendicectomy. Lancet1:22, 1973

    Google Scholar 

  11. Rickett, J.S., Jackson, B.I.: Topical ampicillin in the appendicectomy wound: Report of a double-blind trial. Br. Med. J.4:206, 1969

    Google Scholar 

  12. Greenall, M.J., Evans, M., Pollock A.V.: Should you drain a perforated appendix? Br. J. Surg.65:880, 1978

    Google Scholar 

  13. Davidson, A.I.G., Clark, C., Smith, G.: Postoperative wound infection: A computer analysis. Br. J. Surg.58:333, 1971

    Google Scholar 

  14. Stone, H.H., Sanders, S.L., Martin, J.D.: Perforated appendicitis in children. Surgery69:673, 1971

    Google Scholar 

  15. Leigh, D.A., Simmons, K., Norman E.: Bacterial flora of the appendix fossa in appendicitis and postoperative wound infection. J. Clin. Pathol.27:997, 1974

    Google Scholar 

  16. Raahave, D.: Effects of plastic skin and wound drapes on the density of bacteria in operation wounds. Br. J. Surg.63:421, 1976

    Google Scholar 

  17. Yates, J.L.: An experimental study of the local effects of peritoneal drainage. Surg. Gynecol. Obstet.1:473, 1905

    Google Scholar 

  18. Silen, W.: Colon and Rectum. The Year Book of Surgery. Chicago, Year Book Medical Publishers, 1980, pp. 378–380

    Google Scholar 

  19. Antimicrobial prophylaxis for surgery. Med. Lett. Drugs. Ther.25:77, 1981

    Google Scholar 

  20. Mountain, J.C., Seal, P.W.: Topical ampicillin in grid iron appendicectomy wounds. Br. J. Clin. Pract.24:111, 1979

    Google Scholar 

  21. Nichols, R.L.: Postoperative wound infection. N. Engl. J. Med.307:1701, 1982

    Google Scholar 

  22. Burke, J.F.: The effective period of preventive antibiotic action in experimental incisions and dermal incisions. Surgery50:161, 1961

    Google Scholar 

  23. Condon, R.E., Anderson, M.J.: Diarrhea and colitis in clindamycin-treated surgical patients. Arch. Surg.113:794, 1978

    Google Scholar 

  24. Walt, A.: The appendix. In Operative Surgery, Principles and Technique. Philadelphia, Lea and Febiger, 1972, pp. 477–479

    Google Scholar 

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Gaffney, P.R. Wound infections in appendicitis: Effective prophylaxis. World J. Surg. 8, 287–291 (1984). https://doi.org/10.1007/BF01655054

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