Abstract
Parencbymal cell mass determination with a density gradient technique was used as a supplement to the histological examination of parathyroid glands in a series of patients operated on for hyperparathyroidism. The parenchymal cell mass was easily determined intraoperatively and constituted an objective parameter in the differentiation between normal and abnormal parathyroid glands. It is suggested that such objective determinations of the parenchymal cell mass should be considered in parathyroid histological diagnosis.
Résumé
Dans un groupe de malades opérés d'hyperparathyroÏdie, nous avons mesuré, par gradient de densité, la masse des cellules parenchymateuses et l'avons confrontée à l'examen histologique des parathyroÏdes. La masse des cellules parenchymateuses peut Être aisément mesurée en cours d'opération; elle constitue un paramètre objectif pour différencier les glandes parathyroÏdes normales et anormales. Nous estimons que de telles observations objectives de la masse parenchymateuse devraient Être un des éléments du diagnostic histologique des affections parathyroÏdiennes.
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åkerström, G., Grimelius, L., Johansson, H., Lundqvist, H.: Estimation of the parenchymal cell content of the parathyroid gland, using density gradient columns (brief report). Acta Pathol. Microbiol. Scand. [A]85:555, 1977
åkerström, G., Pertoft, H., Grimelius, L., Johansson, H.: Density determinations of human parathyroid glands by density gradients. Acta Pathol. Microbiol. Scand. [A]87:91, 1979
åkerström, G., Grimelius, L., Johansson, H, Lundqvist, H., Pertoft, H.: Estimation of the parathyroid parenchymal cell mass by density gradients. Am. J. Pathol.In press
åkerström, G., Grimelius, L., Johansson, H, Lundqvist, H., Pertoft, H.: The parenchymal cell mass in normal parathyroid glands.In press
Wang, C., Rieder, S.V.: A density test for the intraoperative differentiation of parathyroid hyperplasia from neoplasia. Ann. Surg.187:63, 1978
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Supported by the Swedish Medical Research Council (project Nos. B80-17X-04787-05B and B80-12X-05662-01 and “Förenade Liv”, Mutual Group Life Insurance Company, Stockholm, Sweden.
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åkerström, G., Grimelius, L., Johansson, H. et al. Parenchymal cell mass determination in parathyroid glands and its application in a material of hyperparathyroidism. World J. Surg. 5, 555–563 (1981). https://doi.org/10.1007/BF01655010
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DOI: https://doi.org/10.1007/BF01655010