Abstract
The term early colorectal carcinoma is used for an infiltrating carcinoma with submucosal spread, but no involvement of the muscle coat (muscularis propria). Our experience with 249 such tumours is reported. Lymph node metastases were detected in only 3% of 130 patients subjected to classical surgery. Early colorectal carcinoma represents a cancer stage with an excellent prognosis (agecorrected 10-year survival rate 100%). The survival rates after limited therapeutic procedures (endoscopic polypectomy, local surgical excision, segmental/tubular resection) or after classical radical surgery do not differ significantly provided that certain selection criteria are strictly observed.
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References
Burghardt E, Holzer E (1982) Minimal invasive cancer (microcarcinoma). Clin Oncol 1:313–645
Hermanek P (1982) Early stages of colorectal carcinoma: morphology, clinical aspects and prognosis. Clin Oncol 1:587–598
Grinnell RS, Lane N (1958) Benign and malignant adenomatous polyps and papillary adenomas of the colon and rectum. An analysis of 1856 tumours in 1335 patients. Surg Gynecol Obstet 106:519–538
Wolff WI, Shinya H (1975) Endoscopic polypectomy: therapeutic and clinicopathologic aspects. Cancer 36:683–690
Morson BC, Bussey HJR, Samoorian S (1977) Policy of local excision for early cancer of the colorectum. Gut 18:1045–1050
Bokelmann D (1978) Tiefsitzendes Rektum-Frühkarzinom: Exstirpationsverfahren. Langenbecks Arch Chir 347:613–617
Cooper HS (1983) Surgical pathology of endoscopically removed malignant polyps of the colon and rectum. Am J Surg Pathol 7:613–623
Morson BC, Whiteway JE, Jones EA, Macrae FA, Williams CB (1984) Histopathology and prognosis of malignant colorectal polyps treated by endoscopic polypectomy. Gut 25: 437–444
Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD (1985) Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. Gastroenterology 89:328–336
Hermanek P (1983) Pathohistologische Begutachtung von Tumoren. Perimed, Erlangen
Morson BC, Sobin LH (1976) Histological typing of intestinal tumours. WHO, Geneva
Hermanek P, Karrer K (1983) Atlas of colorectal tumours. Butterworths, London
Nivatvongs S, Goldberg SM (1978) Management of patients who have polyps containing invasive carcinoma removed via colonoscope. Dis Colon Rect 21:8–11
Shatney CH, Lober PH, Gilbertsen VA, Sosin H (1974) The treatment of pedunculated adenomatous colorectal polyps with focal cancer. Surg Gynecol Obstet 139:845–850
Wolff WI, Shinya H (1975) Definitive treatment of “malignant” polyps of the colon. Ann Surg 182:516–525
Shatney CH, Lober PH, Silberston V, Sosin H (1976) Management of focally malignant pedunculated adenomatous colorectal polyps. Dis Colon Rect 19:334–341
Coutsoftides T, Sivak MV, Benjamin SP, Jagelman D (1978) Colonoscopy and the management of polyps containing invasive carcinoma. Ann Surg 188:638–641
Gillespie PE, Chambers TJ, Chan KW, Doronzo F, Morson BC, Williams CB (1979) Colonic adenomas — a colonoscopic survey. Gut 20:240–245
Riddell RH (1983) Premalignant and early invasive lesions of the colon. In: American Society of colon and rectal surgeons: Colorectal electives syllabus. Boston
Conte ChC, Welch JP, Forouhar F, Bloom GP (1985) Management of endoscopically removed malignant colon polyps — 84th Anual Meeting of the American Society of Colon and Rectal Surgeries, San Diego. Abstracts, p. 10.6
Dewey P, Seifart W (1985) Peranale Lokalbehandlung des Rektumfrühkarzinoms. Zentralbl Chir 110:137–141
Colacchio TA, Forde KA, Scantlebury VP (1981) Endoscopic polypectomy. Inadequate treatment for invasive colorectal carcinoma. Ann Surg 194:704–707
Copeland EM, Miller LD, Jones RS (1968) Prognostic factors in carcinoma of the colon and rectum. Am J Surg 116: 875–881
Kobayashi S, Kasugai T (1973) Polypoid lesions of the colon and rectum with special reference of early detection of polypoid cancer. Endoscopy 5:117–120
Lockhart-Mummery HE, Dukes CE (1952) The surgical treatment of malignant rectal polyps. Lancet 2:751–755
Montori A (1984) Colorectal polyps with invasive carcinoma — a surgical point of view. Colo-proctology 6:281
Morson BC (1966) Factors influencing the prognosis of early cancer of the rectum. Proc R Soc Med 59:607–608
Seib, H-J (1986) Kolonadenome mit invasivem, die L. submucosa infiltrierendem Adenokarzinom. Risiko von Lymphknotenmetastasen und Indikation zur sekundären Operation. Verh Dtsch Ges Pathol 69:683
Welch CE, McKittrick JB, Behringer G (1952) Polyps of the rectum and colon and their relation to cancer. N Engl J Med 247:959–965
Wingard BA, Coller JA, Schoetz DJ, Veidenheimer MC (1985) When is polypectomy enough? 84th Annual Meeting of the American Society of Colon and Rectal Surgeons, San Diego. Abstracts, p 105
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Hermanek, P., Gall, F.P. Early (microinvasive) colorectal carcinoma. Int J Colorect Dis 1, 79–84 (1986). https://doi.org/10.1007/BF01648411
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DOI: https://doi.org/10.1007/BF01648411