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The in vitro activity of flomoxef compared to four other cephalosporins and imipenem

In-vitro Aktivität von Flomoxef im Vergleich mit vier Cephalosporinen und Imipenem

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Summary

The antibacterial activity of the oxacephalosporin flomoxef was evaluated in comparison to cefpirome, cefuzoname, cefotaxime, ceftazidime, and imipenem against fresh clinical isolates. Flomoxef is an antibiotic with strong antibacterial activity against staphylococci including methicillin-resistant strains and streptococci with the exception ofEnterococcus faecalis andEnterococcus faecium. It is very active against gram-negative cocci and rods including gram-positive and gram-negative anaerobes. AgainstPseudomonas sp. flomoxef has no activity.

Zusammenfassung

Verglichen wurde dieIn-vitro-Aktivität von Flomoxef, Cefpirom, Cefuzonam, Cefotaxim, Ceftazidim und Imipenem gegenüber frischen klinischen Stämmen. Flomoxef zeigt eine starke antibakterielle Aktivität gegenüber Staphylokokken (auch Methicillin resistente) und Streptokokken mit der Ausnahme vonEnterococcus faecalis undEnterococcus faecium. Es ist ebenfalls aktiv gengenüber aeroben und anaeroben gram-negativen und gram-positiven Stäbchen und Kokken. Resistent sind Pseudomonaden.

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Authors and Affiliations

  1. Klinikum der Johann Wolfgang Goethe-Universität, Theodor Stern-Kai 7, W-6000, Frankfurt am Main 70, Germany

    P. M. Shah &  H. Knothe

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  1. P. M. Shah
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  2. H. Knothe
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Shah, P.M., Knothe, H. The in vitro activity of flomoxef compared to four other cephalosporins and imipenem. Infection 19 (Suppl 5), S279–S283 (1991). https://doi.org/10.1007/BF01645540

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  • DOI: https://doi.org/10.1007/BF01645540

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