Summary
The problem of the classification of the tumours of the pineal parenchyma or its germ cells is discussed under special consideration of the possibility of distinguishing two categories of the “two cell type” (anisomorphous) tumor: the germinoma and the pineocytoma (the “pinealoma” in the classical concept). The formerly so-called pinealomas and ectopic pinealomas are discussed.
Zusammenfassung
Das Problem der Klassifikation der Tumoren des Pinealisparenchyms oder seiner Keimzellen wird diskutiert unter besonderer Berücksichtigung der Möglichkeit, zwei verschiedene Typen bei den “Zwei-Zell-Tumoren” zu unterscheiden: das Germinom und das (anisomorphe) Pineocytom, das “Pinealom” der klassischen Literatur. Die früher sogenannten Pinealome und ektopischen Pinealome werden diskutiert.
References
Akamatu, H.: Ein Fall von primärem Pinealom aus der Hypothalmus-Infundibulargegend. Gann. 33 (1939) 371–381
Arseni, C., N. Carp: Anatomia patologica a tumorilor sistemului nervos. Editura Didactica si Pedagogica, Bukarest 1978
Bailey, P., H. Cushing: A classification of the tumors of the glioma group on a histogenetic basis with a correlated study of prognosis. J. P. Lippincott, Philadelphia 1926
Bargmann, W.: Die Epiphysis cerebri — Die Entwicklung der Epiphyse (Mensch, Säugetiere). In: Handbuch der mikroskop. Anatomie des Menschen, Bd. VI/4. Springer, Berlin 1943
Berblinger, W.: Zur Kenntnis der Pinealocytome nebst Bemerkungen über die cerebrogene Frühreife. Schweiz. Z. Path. 7 (1944) 107–128
Bookallil, A. J.: Tumours of the pineal region. — A review of 49 cases. Abstracts 5th Congr. Europ. Assoc. Neurosurg. Societies, Oxford 1975, 79–81
Cravioto, H., D. Dart: The ultrastructure of “pinealoma” (seminoma-like tumor of the pineal region). J. Neuropath. exp. Neurol. 32 (1973) 552–565
Cuneo, H. M.: Ectopic pinealomas. J. Neurosurg. 17 (1960) 161–165
Cushing, H.: Intracranial tumors. Charles C Thomas, Springfield 1932
Dayan, A. D., A. H. E. Miller, A. A. Miller, F. J. Pick, N. E. Rankin: Atypical teratomas of the pineal and hypothalamus. J. Path. Bact. 92 (1966) 1–28
Girolami, U. de, H. Schmidek: Clinicopathological study of 53 tumors of the pineal region. J. Neurosurg. 39 (1973) 455–462
Dixon, F. J., R. A. Moore: Tumors of the male sex organs. Armed Forces Institute of Pathology, Washington 1952
Dixon, F. J., jr., R. A. Moore: Testicular tumors — A clinico-pathologic study. Cancer 6 (1953) 427–454
Ewing, G.: Neoplastic Diseases. 3rd Edition. W. B. Saunders, Philadelphia 1928
Ford, F. R., W. Muncie: Malignant tumor within the third ventricle (Three cases of unusual type with invasion of the ventricular walls). Arch. Neurol. Psychiat. (Chic.) 39 (1938) 82–95
Friedman, N. B.: Germinoma of the pineal — Its identity with germinoma (“seminoma”) of the testis. Cancer Res. 7 (1947) 363–368
Friedman, N. B.: The comparative morphogenesis of the extragenital and gonadal teratoid tumors. Cancer 4 (1951) 265–276
Friedman, E. D., A. Plaut: Tumor of the pineal gland (pinealocytoma) with meningeal and neural metastases. Arch. Neurol. Psychiat. (Chic.) 33 (1935) 1324–1341
Globus, H. J., S. Silbert: Pinealomas. Arch. Neurol. Psychiat. (Chic.) 25 (1931) 937–985
Greitz, T.: Tumours of the quadrigeminal plate and adjacent structures. Acta radiol. Diagn. (Stockh.) 12 (1972) 513–528
Harris, W., H. Cairns: Diagnosis and treatment of pineal tumours. With a report of a case. Lancet 1 (1932) 3–9
Henschen, F.: Tumoren des ZNS und seiner Hüllen. In: Lubarsch, O., F. Henke, R. Rössle: Handbuch der speziellen pathologischen Anatomie und Histologie, Bd. XIII/3. Springer, Berlin 1955, 413–1040
Hertig, A. T., H. Gore: Tumors of the female sex organs. Part 3: Tumors of the ovary and fallopian tube. Armed Forces Institute of Pathology, Washington 1961
Horrax, G., P. Bailey: Tumors of the pineal body. Arch. Neurol. Psychiat. (Chic.) 3 (1925) 423
Horrax, G., J. P. Wyatt: Ectopic pinealomas in the chiasmal region. Report of three cases. J. Neurosurg. 4 (1947) 309–326
Hortega, P. Del Rio: Pineal Gland. In: Penfield, W.: Cytology and cellular pathology of the nervous system. Hoeber, New York 1932, Vol. 2, 635–703
Hortega, P. Del Rio: Nomenclatura y clasificacion de los tumores del sistema nervioso. Lopez & Etchefoyen, Buenos Aires 1945
Ishii, R., T. Tsuchida, H. Honda, K. Ueki, Y. Oyake: Radiation therapy and surgical management of pineal tumors. Follow up study of 96 patients. Neurol. Surg. 4 (1976) 263–270
Jänisch, W., H. Güthert, D. Schreiber: Pathologie der Tumoren des Zentralnervensystems. VEB Gustav Fischer-Verlag, Jena 1976
Jennett, B., R. Johnson, R. Reid: Positive contrast ventriculography of pineal region tumours. Acta radiol. Diagn. (Stockh.) 1 (1963) 857–871
Kalm, H., R. Magun: Beitrag zur Klinik und pathologischen Anatomie der Pinealome. Dtsch. Z. Nervenheilk. 164 (1950) 453–468
Kappers, J. A.: The mammalian pineal gland, a survey. Acta neurochir. (Wien) 34 (1976) 109–149
Katsura, S., J. Suzuki, T. Wada: A statistical study of brain tumors in the neurosurgical clinics in Japan. J. Neurosurg. 16 (1959) 570–580
Kernohan, J. W., G. P. Sayre: Tumors of the Central Nervous System. Armed Forces Institute of Pathology, Washington 1952
Kleinsasser, O., O. Kloss: Zur Frage der ektopischen Pinealome. Acta neurochir. (Wien) 6 (1958) 20–29
Krabbe, K. H.: The pineal gland, especially in relation to the problem of its supposed significance in sexual development. Endocrinology 7 (1923) 379–414
Krayenbühl, H., H. V. Zollinger: Malignes metastasierendes Pinealozytom mit dem Bild der Dystrophia adiposo-genitalis. Schweiz. Arch. Neurol. Psychiat. 51 (1943) 77–98
Lichtenstein, B. W.: A textbook of neurophathology. With clinical, anatomical and technical supplements. W. B. Saunders Comp., Philadelphia 1949, 474
MacKay, R. P.: Pinealoma of diffuse ependymal origin. Arch. Neurol. Psychiat. (Chic.) 42 (1939) 892–901
Markesbery, W. R., W. H. Brooks, L. Milsow, R. H. Mortara: Ultrastructural study of the pineal germinoma in vivo and in vitro. Cancer 37 (1976) 327–337
McGovern, V. J.: Tumours of the epiphysis cerebri. J. Path. Bact. 61 (1949) 1–9
Nielsen, S. L., C. B. Wilson: Ultrastructure of a “pineocytoma”. J. Neuropath. exp. Neurol. 34 (1975) 148–158
Obrador, S., Y. J. Sanz Ibanez: Tumores intracraneales. Editorial Paz Montalvo, Madrid 1955
Obrador, S., M. Soto, J. A. Gutierrez-Diaz: Surgical management of tumours of the pineal region. Acta neurochir. (Wien) 34 (1976) 159–171
Olivecrona, H.: The surgical treatment of intracranial tumors. In: Olivercrona, H., W. Tönnis: Handbuch der Neurochirurgie, Bd. IV/4. Springer-Verlag, Berlin, Heidelberg, New York 1967, 1–301
Phalakornkule, S., M. W. Woodruff: Extragonadal retroperitoneal seminoma. J. Urol. 91 (1964) 579–581
Pierce, G. B.: Ultrastructure of human testicular tumors. Cancer 19 (1966) 1963–1983
Polvani, F.: Studio anatomico della glandola pineale umana. Folia neuro-biol. (Lpz.) 7 (1913) 655–695
Ringertz, N., H. Nordenstam, G. Flyer: Tumors of the pineal region. J. Neuropath. exp. Neurol. 13 (1954) 540–561
Riverson, E., C. V. Brunngraber, K. J. Zülch: Beitrag zur Frage der “ektopischen Pinealome”. Zbl. Neurochir. 34 (1973) 31–40
Rubinstein, L. J.: Tumors of the central nervous system. Armed Forces Institute of Pathology, Washington 1972, 268–284
Rubinstein, L. J.: Presidential Address. J. Neuropath exp. Neurol. 31 (1972) 7–26
Russell, D. S.: The pinealoma: Its relationship to teratoma. J. Path. Bact. 56 (1944) 145–150
Russell, D. S.: “Ectopic pinealoma”: Its kinship to atypical teratoma of the pineal gland. Report of a case J. Path. Bact. 68 (1954) 125–129
Russell, D. S., L. J. Rubinstein: Pathology of tumours of the nervous system. 3rd Edition. Edward Arnolo Ltd., London 1971
Sano, K.: Diagnosis and treatment of tumours in the pineal region. Acta neurochir. (Wien) 34 (1976) 153–157
Staemmler, M.: 1934 (cited in Warzok, R., H. Arnold (65)).
Tabuchi, K., O. Yamada, A. Nishimoto: The ultrastructure of pinealomas. Acta neuropath. (Berl.) 24 (1973) 117–127
Tani, E., K. Ikeda, K. Susumu, S. Yamagata, M. Nishiura, N. Higashi: Specialized intercellular junctions in human intracranial germinomas. Acta neuropath. (Berl.) 27 (1974) 139–151
Troland, C. E., G. A. Brown: Precocious puberty of intracranial origin. J. Neurosurg. 5 (1948) 541–555
Turkewitsch, N.: Die Entwicklung der Zirbeldrüse des Menschen. In: Göpfert, E.: Gegenbauers morpholog. Jahrb., Bd. 72. Akademische Verlagsgesellschaft, Leipzig 1933, 379–445
Unio Internationalis Contra Cancrum (UICC): Histologische Nomenklatur menschlicher Tumoren. Zschr. Krebsforsch. 63 (1959) 75–98
Unio Internationalis Contra Cancrum (UICC): Cancer incidence in five continents. Springer-Verlag, Berlin, Heidelberg, New York 1966/1969
Walton, K.: Teratomas of the pineal region and their relationship to pinealomas. J. Path. Bact. 61 (1949) 11–21
Warzok, W., H. Arnold: Zur Problematik der intrakraniellen Dysgerminome. Zbl. allg. Path. path. Anat. 115 (1972) 67–73
Werner, T.: Ein Pinealom mit diffuser Metastasierung in die Meningen. Zbl. Neurochir. 4 (1939) 155–160
Yonemasu, Y., K. Kitamura, K. Okudera: Tumors in the pineal region. — A clinicopathological study of 77 cases. Abstracts 5th Congr. Europ. Assoc. Neurosurg. Societies, Oxford 1975, 124–126
Zülch, K. J.: Biologie und Pathologie der Hirngeschwülste. In: Olivecrona, H., W. Tönnis: Handbuch der Neurochirurgie, Bd. III. Springer-Verlag, Berlin, Heidelberg, New York 1956
Zülch, K. J.: Morphologische Veränderungen an Geschwülsten nach Bestrahlung und Schädigungsmöglichkeiten am normalen Hirn. In: Meyer, H., J. Becker: Strahlenforschung und Strahlenbehandlung, Bd. IV. Urban & Schwarzenberg, München, Berlin 1963, 47–62
Zülch, K. J.: Brain Tumours — Their Biology and Pathology. 2nd Edition. Springer Publishing Comp. Inc., New York 1965
Zülch, K. J.: Roentgen sensitivity of cerebral tumours and so-called late irradiation necrosis of the brain. Acta radiol. Ther. Phys. Biol. 8 (1969) 92–110
Zülch, K. J.: Histological Typing of Tumours of the Central Nervous System. International Histological Classification of Tumours, No. 22. World Health Organization, Geneva 1979 (in press)
Zülch, K. J., A. L. Woolf: Classification of Brain Tumors. The 1st Kölner Symposium. Acta neurochir. (Wien), Suppl. X. Springer-Verlag, Wien 1964
Zülch, K. J.: Atlas of gross neurosurgical pathology. Springer-Verlag, Berlin, Heidelberg, New York, 1975
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Riverson, E.A., Zülch, K.J. Pineal parenchymal tumours and germinomas (the problem of the so-called pinealomas). Neurosurg. Rev. 2, 3–11 (1979). https://doi.org/10.1007/BF01644041
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DOI: https://doi.org/10.1007/BF01644041