Summary
The mortality in listeric meningitis and septicaemia, the two main clinical manifestations of the infection, is generally considered to be high. However, co-existing disorders rather than the listeric infection itself seem to determine the outcome. In the present study of 72 listeric infections among non-pregnant adults, 28 patients without co-existing disease had a fatality rate of 10.7% as compared to 57.9% among 19 immunocompromised individuals. Finally, in a third group of listeric patients, including alcoholics and people with heart disease or diabetes mellitus, the fatality rate was 24.0%.
Zusammenfassung
Die Letalität bei Listeriose-Meningitis und -Sepsis, den beiden Hauptmanifestationen der Infektion, ist nach allgemeiner Ansicht hoch. Jedoch scheinen eher die Begleiterkrankungen als die Listeriose-Infektion selbst den Ausgang der Erkrankung zu bestimmen. In der vorliegenden Studie an 72 Fällen mit Listeriose-Infektion bei nicht schwangeren Erwachsenen betrug die Letalität bei 28 Patienten ohne Begleitkrankheit 10,7%, bei 19 Patienten mit gestörter Immunität hingegen 57,9%. In einer dritten Gruppe von Listeriose-Kranken, die Alkoholiker, Patienten mit Herzerkrankungen und Diabetes mellitus einschloß, lag die Sterberate bei 24,0%.
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Iwarson, S., Larsson, S. Outcome of listeria monocytogenes infection in compromised and non-compromised adults. Infection 7, 54–56 (1979). https://doi.org/10.1007/BF01641612
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DOI: https://doi.org/10.1007/BF01641612