Summary
We report a case of pulmonary hypoplasia associated with renal agenesia diagnosed in a 46-year-old woman admitted to hospital because of a viral pleuro-pericarditis. The chest x-ray raised the suspicion of left pulmonary hypolasia. The CT scan and the Magnetic Resonance Image confirmed the presence of the congenital lung malformation and detected the absence of the left kidney. The clinical presentation, radiological diagnosis and embryological basis are described.
Résumé
Nous présentons un cas d'hypoplasie pulmonaire associée à une agénésie rénale diagnostiquées chez une femme de 46 ans admise à l'hôpital pour une pleuro-péricardite virale. Le cliché radiologique du thorax fait suspecter une hypoplasie pulmonaire gauche. La tomodensitométrie et l'image par résonance magnétique nucléaire confirment la présence d'une malformation pulmonaire et montrent l'absence du rein gauche. La présentation clinique, le diagnostic radiologique et les bases embryologiques sont décrites.
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References
Glick PL, Siebert JR, Benjamin DR (1990) Pathophysiology of congenital diaphragmatic hernia: I. Renal enlargement suggests feedback modulation by pulmonary derived renotropins-A unifying hypothesis to explain pulmonary hypoplasia, polyhydramnios, and renal enlargement in fetus/newborn with congenital diaphragmatic hernia. J Pediatr Surg 25: 492–495
Hosoda Y, Rossman JE, Glick PL (1993) Pathophysiology of congenital diaphragmatic hernia IV: renal hyperplasia is associated with pulmonary hypoplasia. J Pediatr Surg 28: 464–470
Källen B, Winberg J (1974) Caudal mesoderm pattern of anomalies: from renal agenesis to sirenomelia. Teratology 9: 99–112
Larsen WJ (1993) Human Embryology. Churchill Livingstone, New York, pp 111–125 and 235–247
Maltz DL, Nadas AS (1968) Agenesis of the lung. Presentation of eight new cases and review of the literature. Pediatrics 42: 175–188
Mata JM, Cáceres J, Lucaya J, García-Conesa JA (1990) CT of congenital malformations of the lung. Radiographics 10: 651–674
Nakamura Y, Harada K, Yamamoto I, Uemura Y, Okamoto K, Fukuda S, Hashimoto T (1992) Human pulmonary hypoplasia: statistical, morphological, morphometric and biochemical study. Arch Pathol Lab Med 116: 635–642
Nicolini U, Fisk NM, Rodech CH, Talbert DG, Wigglesworth JS (1989) Low amniotic pressure in oligohydramnios is this the cause of pulmonary hypoplasia? Am J Obstet Gynecol 161: 1098–1101
O'Rahilly R, Muecke EC (1972) The timing and sequence of events in the development of the human urinary system during the embryonic period proper. Z Anat Entwickl Gesch 138: 99–109
O'Rahilly R, Boyden EA (1973) The timing and sequence of events in the development of the human respiratory system during the embryonic period proper. Z Anat Entwickl Gesch 141: 237–250
Osborne J, Masel J, McCredie J (1989) A spectrum of skeletal anomalies associated with pulmonary agenesis: possible neural crest injuries. Pediatr Radiol 19: 425–432
Petters GA, Reid LM, Docimo S, Luetic T, Carr M, Retik AB, Mandel J (1991) Role of the kidney in lung growth and maturation in the setting of obstructive uropathy and oligohydraminos. J Urol 146: 597–600
Potter EL (1974) Normal and abnormal development of the kidney. Year Book, Chicago, pp 1–200
Sañudo JR, Domenech-Mateu JM (1990) The laryngeal primordium. A new explanation. J Anat 175: 207–222
Smith R, Bech AO (1958) Agenesis of the lung. Thorax 13: 28–33
Soulen RL, Cohen RV (1979) Selected reports: plain film recognition of pulmonary agenesis in the adult. Chest 60: 185–187
Spooner BS, Wessels NK (1970) Mammalian lung development: interactions in primordium formation and bronquial morphogenesis. J Exp Zool 175: 445–454
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Mirapeix, R., Domingo, C., Saũdo, J. et al. Unusual association of two unilateral anomalies present in adulthood: pulmonary hypoplasia and renal agenesis. Surg Radiol Anat 17, 177–179 (1995). https://doi.org/10.1007/BF01627581
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DOI: https://doi.org/10.1007/BF01627581