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Study of bone mineral density in lumbar spine and femoral neck in a Spanish population

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Abstract

The aim of this study was to generate standard curves for bone mineral density (BMD) in a Spanish population using dual-energy X-ray absorptiometry (DXA), at both lumbar spine and femoral neck sites. The total sample size was 2442 subjects of both sexes aged 20–80 years, stratified according to survival rates, demographic distribution by local regions and sex ratio in the Spanish population. Subjects with suspected conditions affecting bone metabolism or receiving any treatment affecting bone mineralization were excluded. The study was carried out in 14 hospitals and bone density measurements were performed, using a QDR/1000 Hologic device. In the female population, the highest value for lumbar spine BMD was found within the 30–39 years age group, being significantly lower after the age of 49 years. In the male population, the highest values for lumbar spine BMD are found one decade earlier than in the female population and become significantly lower after the age of 69 years. The highest values for femoral neck BMD in men and women was found in the 20–29 year age group. Values for femoral neck BMD in the female population become statistically lower after the age of 49 years, while in the male population this effect was seen after the age of 69 years. Values for femoral neck BMD were higher in men than women at all ages.

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Authors and Affiliations

  1. Jefe del Departamento de Bioestadística, Universidad Aut ónoma, Madrid

    J. L. Carrasco de la Peña

  2. Jefe Servicio Farmacología Clínica, Clinica Universidad de Navarra, Pamplona

    J. Honorato Perez

  3. Catedratico de Patología Médica, Universidad de Sevilla, Spain

    R. Perez Cano

  4. Jefe Unidad Metabolica, Fundación Jimenez Diaz, Madrid

    A. Rapado

  5. Rhóne-Poulenc Rorer S.A. Alcorcón, Madrid, Spain

    I. Ruiz Martinez

  6. Jefe Asociada, Unidad Metabolica, Fundación Jimenez Diaz, Avda. Reyes Católicos, 2, E-28040, Madrid, Spain

    M. Diaz Curiel

Authors
  1. M. Diaz Curiel
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  2. J. L. Carrasco de la Peña
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  3. J. Honorato Perez
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  4. R. Perez Cano
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  5. A. Rapado
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  6. I. Ruiz Martinez
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Additional information

Others investigators of the Multicentre Research Project on Osteoporosis: Drs Torrijos, Aguado, Espinosa (H. La Paz, Madrid); Drs Lozano, Gonzalez (H. Clínico San Carlos, Madrid); Drs Yagüe, López Gavilanes (F. Jimenez Díaz, Madrid); Drs Portugal, Del Pino, Martín (H. Clínico Univ., Salamanda); Drs Roig, Nolla (Ciudad Sanitaria Bellvitge, Barcelona); Drs Farrerons, Lopez Navidad, Yoldi (H. Sta. Creu i San Pau, Barcelona); Drs Diez Pérez, Kanterewicz, Martínez Izquierdo, H. de la Esperanza, Barcelona); Drs. Romeu, Edo, Monzó (H. La Fe, Valencia); Drs Moruno, Vazquez (H. Clínico Univesitario, Sevilla); Drs Escobar, Muñoz Torres, Raya, Salvatierra (H. Clínico Universitario, Granada); Drs Cannata, Gómez Alonso, Virgós (H. Central de Asturias); Drs Ferrer, Peguero (H. Miguel Servet, Zaragoza); Drs Ganoza, Barrios (Clinica Universitaria, Pamplona); Drs Betancor, Sosa Henríquez, Hernandez Hernandez (H. Insular Las Palmas).

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Curiel, M.D., Carrasco de la Peña, J.L., Perez, J.H. et al. Study of bone mineral density in lumbar spine and femoral neck in a Spanish population. Osteoporosis Int 7, 59–64 (1997). https://doi.org/10.1007/BF01623462

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  • DOI: https://doi.org/10.1007/BF01623462

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