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Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors

  • Guest Editorial
  • Experimental Oncology
  • Published:
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Summary

This guest editorial discusses the molecular cytogenetic features of human renal parenchymal tumors with an emphasis on their diagnostic usefulness. Important contributions of this review are discrimination (a) between papillary and nonpapillary renal cell carcinomas and (b) between tubulopapillary adenomas and papillary carcinomas. Speculations regarding the histogenesis of different renal parenchymal tumors are presented, with the hope that they may serve to diminish some of the confusion surrounding the classification of these tumors.

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Abbreviations

RCC:

renal cell carcinoma

VHL:

von Hippel-Lindau disease

EGFR:

epidermal growth factor receptor

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Authors and Affiliations

  1. Biological Carcinogenesis and Development Program, Program Resources Inc., National Cancer Institute, Frederick Cancer Research Facility, 21701, Frederick, MD, USA

    Gyula Kovacs

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  1. Gyula Kovacs
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The “Journal of Cancer Research and Clinical Oncology” publishes in loose succession “Editorials” and “Guest editorials” on current and/or controversial problems in experimental and clinical oncology. These contributions represent exclusively the personal opinion of the author The Editors

By acceptance of this article, the publisher or recipient acknowledges the right of the U.S. Government to retain a nonexclusive, royalty-free license in and to any copyright covering the article. This project has been supported by a grant of the German Research Council (Ko 841/3) and at least in part with Federal funds from the Department of Health and Human Services under contract number NO-CO-74102 with Program Resources Inc. The content of this publication does not necessarily reflect the views or policies of the Department of Health and Human Services, nor does mention of trade names, commecial products, or organisations imply endorsement by the U.S. Government

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Kovacs, G. Application of molecular cytogenetic techniques to the evaluation of renal parenchymal tumors. J Cancer Res Clin Oncol 116, 318–323 (1990). https://doi.org/10.1007/BF01612912

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  • DOI: https://doi.org/10.1007/BF01612912

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