Abstract
Primary extraskeletal epithelial neoplasms with osteoclast-like giant cells are rare. We describe a case of renal cell carcinoma with a sarcomatoid component and non-neoplastic osteoclast-like giant cells. The giant cells were noted in both the conventional and the sarcomatoid components of the neoplasm. Immunohistochemical studies indicate that these cells are monocyte/histiocyte in origin and most probably a host stromal reaction to the neoplasm.
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El-Naggar, A.K., Gaber, K. & Ordonez, N.G. Renal cell carcinoma with osteoclast-like giant cells. Vichows Archiv A Pathol Anat 422, 427–431 (1993). https://doi.org/10.1007/BF01605464
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DOI: https://doi.org/10.1007/BF01605464