Summary
We report a malignant uterine paraganglioma in a 40-year-old female, who died 7 months after the initial diagnosis. On light microscopy the tumour showed a typicalzellballen pattern as well as a pronounced cellular pleomorphism. In many tumour cells hyaline globules were demonstrated within the cytoplasm. Immunohistochemically the lesion was characterized by the presence of neuron-specific enolase, protein gene product 9.5 and synaptophysin, and electron microscopically by the occurrence of neurosecretory granules.
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Beham, A., Schmid, C., Fletcher, C.D.M. et al. Malignant paraganglioma of the uterus. Vichows Archiv A Pathol Anat 420, 453–457 (1992). https://doi.org/10.1007/BF01600518
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DOI: https://doi.org/10.1007/BF01600518