Abstract
Studies with crosses of inbred chicken lines demonstrate that resistance to Marek's disease, a herpesvirus-induced lymphoma of chickens, is associated with an allele (B 21) of the major histocompatibility locus (theB locus). TheB 21 allele is thus the first genetic marker for resistance to herpesvirus-induced neoplastic disease, and our studies suggest the means whereby similar associations might be found in man.
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Longenecker, B.M., Pazderka, F., Gavora, J.S. et al. Lymphoma induced by herpesvirus: Resistance associated with a major histocompatibility gene. Immunogenetics 3, 401–407 (1976). https://doi.org/10.1007/BF01576971
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DOI: https://doi.org/10.1007/BF01576971