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A new mycobactin, mycobactin J, fromMycobacterium paratuberculosis

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Abstract

This paper reports the production, purification, and biological assay of a new mycobactin fromMycobacterium paratuberculosis. This new mycobactin, designated mycobactin J, is produced by a strain ofM. paratuberculosis adapted to growth on synthetic medium without exogenous mycobactin. Mycobactin J reduces the incubation period ofM. paratuberculosis in complex medium by 3 weeks when compared with medium containing mycobactin P, and a higher proportion of the organisms, in inocula from infected tissues or fecal specimens, produce colonies. Also, some strains ofM. paratuberculosis will grow on medium containing mycobactin J that will not grow on medium containing mycobactin P.

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Literature Cited

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Authors and Affiliations

  1. National Animal Disease Center, Agricultural Research Service, Science and Education, U.S. Department of Agriculture, P.O. Box 70, 50010, Ames, Iowa, USA

    Richard S. Merkal & Willard G. McCullough

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  1. Richard S. Merkal
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  2. Willard G. McCullough
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Merkal, R.S., McCullough, W.G. A new mycobactin, mycobactin J, fromMycobacterium paratuberculosis . Current Microbiology 7, 333–335 (1982). https://doi.org/10.1007/BF01572599

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  • DOI: https://doi.org/10.1007/BF01572599

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