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Spheroidal degeneration of the cornea

Prevalence and association with other eye diseases

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Abstract

A sample of 2,427 South African Negroes of the Pondo tribe was specifically examined for spheroidal degeneration of the cornea (S.D.C.).

The prevalence of S.D.C. was 7.0% for the whole sample. It was twice as prevalent in men (9.9%) as in women (4.3%) and the prevalence increased with age over 50 for both sexes.

The risk of having developed Stage II and III S.D.C. increased with age for men but not for women. The risk of having developed Stage III S.D.C. was not related to age or sex.

No significant associations were found between S.D.C. and pterygium, cortical or nuclear cataract and glaucoma (all types and absolute glaucoma). There was a significant association between S.D.C. and pseudocapsular exfoliation for elderly men but elderly men with arcus senilis were less likely to have developed S.D.C.

Poor corneal nutrition or metabolism are possible aetiological factors in the progression of S.D.C. to Stages II and III.

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References

  • Bartholomew, R.S. Glaucoma in the negro. A population study among the Pondo tribe.S. Afr. Arch. Ophth. (in press 1977).

  • Cameron, M.E. Pterygium throughout the world. Charles C. Thomas, Springfield, Ill. (1965).

    Google Scholar 

  • Darrell, R.W. & Bachrach, C.A. Pterygium among veterans.Arch. Ophth. 70:158–169 (1963).

    Google Scholar 

  • Duke-Elder, S. System of Ophthalmology, Vol. 8, pp 873. Henry Kimpton, London (1965).

    Google Scholar 

  • Frauenfelder, F.T., Hanna, C. & Parker, J.M. Spheroid degeneration of the cornea and conjunctiva.Am. J. Ophth. 74:821–828 (1972).

    PubMed  Google Scholar 

  • Frauenfelder, F.T. & Hanna, C. Spheroid degeneration of the cornea.Am. J. Ophth. 76:41–50 (1973).

    PubMed  Google Scholar 

  • Freedman, A.: Climatic droplet keratopathy.Arch. Ophth. 89:193–197 (1973).

    Google Scholar 

  • Freedman, J. Nama keratopathy.Brit. J. Ophth. 57:688–691 (1973).

    PubMed  Google Scholar 

  • Hanna, C. & Frauenfelder, F.T. Spheroid degeneration of the corena and conjunctiva.Am. J. Ophth. 74:829–839 (1972).

    PubMed  Google Scholar 

  • Keen, P. The problems and fallacies of field studies in Africa, with special reference to cancer surveys.S. Afr. Med. J. 44:1143–1146 (1970).

    PubMed  Google Scholar 

  • Population Census. Report 02-02-02. Population census 6th May, 1970. The Government Printer, Pretoria (1973).

  • Ringvold, A. On the occurrence of pseudo-exfoliation material in extrabulbar tissue from patients with pseduo-exfoliation syndrome of the eye.Acta Ophth. (Kbh.) 51:411–418 (1973).

    Google Scholar 

  • Rodger, F.C. Clinical findings, course and progress of Bietti's corneal degeneration in the Dahlak Islands.Brit. J. Ophth. 57:657–664 (1973).

    PubMed  Google Scholar 

  • Schapera, I. The bantu speaking tribes of South Africa. George Routledge and Son Ltd, London (1937).

    Google Scholar 

  • Thompson, B.W. The Climate of Africa. Oxford University Press, London (1965).

    Google Scholar 

  • Wilson, M.M. Reaction to Conquest: effects of contact with Europeans on the Pondo of South Africa, 2nd ed. Oxford University Press, London (1961).

    Google Scholar 

  • Wilson, M.M. & Thompson, L. The Oxford History of South Africa. Oxford University Press, London (1969).

    Google Scholar 

  • Young, J.D.H. & Finlay. R.D. Primary spheroidal degeneration of the cornea in Labrador and Newfoundland.Am. J. Ophth. 79:129–134 (1975).

    PubMed  Google Scholar 

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Bartholomew, R.S. Spheroidal degeneration of the cornea. Doc Ophthalmol 43, 325–340 (1977). https://doi.org/10.1007/BF01569202

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