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Butanol tolerance and autobacteriocin production byClostridium acetobutylicum

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Abstract

Serial enrichment was used to obtain a strain ofClostridium acetobutylicum demonstrating a 40% increase in tolerance to added butanol and a further 17% improvement in the ability to produce butanol. The glucose and the butyrate consumption were higher for the G1 variant than for the wild-type strain. In consideration of the higher butanol tolerance, a disappointly low titer of butanol was produced by the new strain. This can be explained by the higher level of autobacteriocin produced by G1. Control of autobacteriocin production appears to be one of the key factors limiting the potential of the acetone butanol fermentation.

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Authors and Affiliations

  1. Department of Biochemical Engineering, National Institute of Applied Sciences, UA-CNRS 544, Toulouse, France

    Philippe Soucaille, Gwenaël Joliff, Anne Izard & Gerard Goma

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  1. Philippe Soucaille
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  2. Gwenaël Joliff
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  3. Anne Izard
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  4. Gerard Goma
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Soucaille, P., Joliff, G., Izard, A. et al. Butanol tolerance and autobacteriocin production byClostridium acetobutylicum . Current Microbiology 14, 295–299 (1987). https://doi.org/10.1007/BF01568139

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  • DOI: https://doi.org/10.1007/BF01568139

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