Abstract
Lp(a), a polymorphic lipoprotein of human serum, has been isolated from strongly positive normal sera. The described procedure utilizes a serum pool of several liters. The purified lipoprotein has been investigated in its intact and totally delipidized form. Protein constituents could be characterized as apolipoprotein-B, apolipoprotein-AIII, and the Lp(a)-specific, dissociable polypeptide. Albumin could only be found in some of the preparations. The Lp(a)-specific polypeptide could be separated and characterized by its amino acid composition.
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Jürgens, G., Kostner, G.M. Studies on the structure of the Lp(a) lipoprotein: Isolation and partial characterization of the Lp(a)-specific antigen. Immunogenetics 1, 560–569 (1974). https://doi.org/10.1007/BF01564093
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DOI: https://doi.org/10.1007/BF01564093