Abstract
The level of circulating Interferon induced in mice by Newcastle disease virus is controlled by a single codominant locus,If-1, with two alleles,If-1 l for low andIf-1 h for high production. This locus is linked to the histocompatibility locusH-28. Of three C57BL/6By lines congenic for the BALB/cBy allele atH-28, two are carrying the BALB/cBy allele and one, the C57BL/6By allele atIf-1. Thus, mouse strains that are genetically very similar but different in their production of NDV-induced circulating Interferon now are available.
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De Maeyer, E., De Maeyer-Guignard, J. & Bailey, D.W. Effect of mouse genotype on interferon production. I. Lines congenic at theIf-1 locus. Immunogenetics 1, 438–443 (1974). https://doi.org/10.1007/BF01564081
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DOI: https://doi.org/10.1007/BF01564081